Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.

Abstract: A compound having formula (1) has excellent heat resistance. In formula (1), X represents a divalent polycyclic condensed ring group having two or more thiophene rings and having an sp3 carbon atom as a constituent element. R1 and R2 each represent an alkyl group, R3 represents an alkyl group, k represents an integer of 0 to 4, and A represents a group having formula (a1), (a2), or (b1): R4, R5, R6, R7, R8, and R9 each represent an alkyl group, E1 and E2 each represent —C(R10)(R11)—, —C(O)—, —O—, or —NR12—. R10 and R11 each represent an alkyl group, R12 represents an alkyl group, m and n each represent 0 or 1, where m+n=1.

Abstract: A control method for gas-shielded arc welding includes providing a normal arc period in which the welding current is maintained at a setting current Icc set in advance, and providing a separation control period after the separation timing of the molten droplet is detected in the normal arc period, the separation control period including a current decreasing section, a current maintaining section, and a current increasing section. In the separation control period, at least one of the following controls for preventing a short circuit is performed: control of an output voltage, control of a feeding speed, and control of a gas ratio.

Abstract: A wiping module includes a wiping portion and a cleaning portion. The wiping portion includes a wiping member wiping a liquid discharge head that discharges a liquid from a nozzle provided on a nozzle surface, a storage support portion supporting the wiping member and configured to store the liquid by the wiping, and a movement support portion mounting the storage support portion and configured to reciprocate along a wiping direction, which is a direction in which the wiping is performed. The cleaning portion cleans the wiping member. The cleaning portion includes a cleaning member and a guide portion guiding the cleaning member. The cleaning member is configured to follow a movement of the wiping portion in the wiping direction and to scrape off the liquid adhering to the wiping member while being guided by the guide portion.

Abstract: An intaglio jig for manufacturing an electronic component having an external electrode by applying a conductive paste to an electronic component body includes an elastic body, and a recessed portion that is formed in the elastic body and in which the conductive paste is contained. The recessed portion includes an opening having an opening width that conforms to a width of the external electrode, a bottom surface at a predetermined depth from the opening, and at least one protrusion portion in which a protrusion height locally protruding from the bottom surface is less than the predetermined depth.

Abstract: An electrically drivable device includes a device body including an actuator and a handle attachable to and detachable from the device body. The handle includes a connector separably connectable with the device body, a pressure receiver displaceable in response to a gripping force with which the user grips the handle, a magnet control mechanism configured to operate a permanent magnet in conjunction with the displacement of the pressure receiver, and a frame holding the pressure receiver in such a manner that the pressure receiver is displaceable, and containing the magnet control mechanism. The device body includes a magnetic sensor configured to, in response to the pressure receiver being displaced with the handle attached to the device body, detect magnetism that the permanent magnet applies through the connector.

Abstract: A method for forming a zeolite membrane by performing an ALD cycle, the ALD cycle including a silicon oxide film forming step and an aluminum oxide film forming step. In the silicon oxide film forming step, an organic Si compound is used as a first raw material gas and OH radicals are used as a reaction gas; in the aluminum oxide film forming step, an organic Al compound is used as a second raw material gas and OH radicals are used as a reaction gas; and the silicon oxide films and the aluminum oxide films are alternately formed in forward or reverse order to form the zeolite membrane.

Abstract: An electric device includes: an electric circuit; a power supply circuit configured to feed electric power to the electric circuit and stop the feed; and a housing containing the electric circuit and the power supply circuit. The power supply circuit is configured to, in response to a first operation performed from outside the housing while the power supply circuit is in an OFF state, the OFF state being a state in which the battery feeds no electric power to the electric circuit, transition to an ON state, the ON state being a state in which the battery continuously feeds electric power to the electric circuit even after an end of the first operation, and in response to a second operation performed while the power supply circuit is in the ON state, transition to the OFF state.

Abstract: A positioning jig assembly includes a positioning main body with holes into which electronic component bodies are respectively press-fit, a first and a second guide bodies disposed to be superimposed on the positioning main body in a planar view. First through-holes are formed in the first guide body. Second through-holes formed in the second guide body guide the electronic component main bodies to the first through-holes. The first through-holes provisionally position the electronic component main bodies. When height in the first direction of the electronic component main bodies is represented as H, lengths of the first through-hole and the second through-hole are respectively represented as L1 and L2, and depth of the hole is represented as D, L1<H<D+L1+L2 and D<H hold.

Abstract: An ALD device includes a first precursor generator that is connected to a processing gas source and generates a first precursor to be supplied to a reactor vessel, and a second precursor generator that is connected to a reducing gas source and the reactor vessel and generates a second precursor to be supplied to the reactor vessel. The first precursor generator etches a target by a first plasma excited by a first plasma generator and supplies a compound gas containing a metallic component as the first precursor. The second precursor generator supplies radicals of a reducing gas component in a second plasma excited by a second plasma generator as the second precursor.

Abstract: In a riding-type mower, a vehicle body includes a rear portion in which a pair of right/left vehicle body frames extend in a front-rear direction relative to the vehicle body, with a gap therebetween in a lateral width direction. A mowing device is configured to discharge mown grass rearward relative to the vehicle body such that the mown grass falls onto the ground. A cover is provided in a bottom portion of the vehicle body, at a position that is rearward of the mowing device, and covers a gap between the pair of right/left vehicle body frames.

Abstract: The invention provides a method for producing methacrylyl-CoA that converts 3-hydroxyisobutyryl-CoA into methacrylyl-CoA using an enzyme having dehydratase activity as a method for producing methacrylyl-CoA using an enzyme catalyst. In this production method, conversion rate of 3-hydroxyisobutyryl-CoA into methacrylyl-CoA by the enzyme having dehydratase activity is 50% or higher. In this production method, furthermore, the enzyme having dehydratase activity derives from a microorganism belonging to the genus Pseudomonas or Rhodococcus.

Abstract: A method for forming films on particles of powder includes diffusing the powder by leading the powder into a jet nozzle and ejecting a jet flow of the powder; leading the diffused particles of powder, a raw material gas, and a reaction gas activated by atmospheric pressure plasma, into a reaction container, and forming a swirl flow in the container; and forming the films on the diffused particles of powder by reaction of a raw material gas and an activated reaction gas in the container. An apparatus is also disclosed having a reaction container with a peripheral wall having a round section in plan view and a jet nozzle for a powder source, raw material gas, and atmospheric pressure plasma sources are coupled to and enter the container at an angle with a radius thereof thereby forming a swirl flow to form a film on the powder.

Abstract: An electronic component manufacturing method includes a blotting process of bringing a conductive paste applied to an end portion of each electronic component body held by a jig into contact with a surface of a surface plate. The blotting process includes simultaneous performance of a distance changing process of changing the distance between an end face of each electronic component body and the surface of the surface plate and a position changing process of changing a two-dimensional position where the end face of the electronic component body is projected on the surface of the surface plate in such a manner that the direction of the movement of two-dimensional position in parallel to the surface of the surface plate successively varies (e.g., along a circular path).

Abstract: A film forming apparatus configured to form a metal oxide film or a metal nitride film through atomic layer deposition by alternately introducing metal compound gas and an OH radical or an NH radical in a reaction container. The film forming apparatus including: the reaction container; and at least one plasma generator provided outside the reaction container and configured to generate a first plasma including an oxygen radical or a nitrogen radical when oxygen or nitrogen is supplied and generate a second plasma including a hydrogen radical when hydrogen is supplied. The OH radical is generated by collision between the oxygen radical and the hydrogen radical or the NH radical is generated by collision between the nitrogen radical and the hydrogen radical in a downstream region from an outlet of the at least one plasma generator to an inner space of the reaction container.

Abstract: Gas-shielded arc welding in which the tip-to-work distance changes is configured so that fluctuations in welding current are curbed while arc length control is maintained. This is achieved with a corrected current calculating unit that includes a first controlling expression where a first gain G1 is multiplied by an instantaneous voltage error value that is the difference between an instantaneous output voltage setting value and an output voltage detection value, and/or a second controlling expression where a second gain G2 is multiplied by an average voltage error value that is the difference between an output voltage setting value and an average output voltage detection value of a pre-set period of time, determines an arc property gain G1 and/or G2 based on a torch position detection value determined by a torch position determinator, and calculates a corrected current based on the first and/or the second controlling expression.

Abstract: A work vehicle includes a cutter device for cutting plant in a field, a storage section for storing plant cut by the cutter device, an inclination angle sensor for detecting an inclination angle ((?d)) of the vehicle body, a display device for displaying the inclination angle detected by the inclination angle sensor, and a reporting device for reporting the inclination angle exceeding a permissible inclination angle ((?a)).

Abstract: A pre-press process includes a first step for bonding a first end portion of each of a plurality of electronic component bodies to a bonding surface of a flat plate material disposed in a jig, a second step for moving the jig relative to a surface plate, a third step for bringing a second end portions of each of the plurality of electronic component bodies into contact with the surface plate while the flat plate material is in a softened state so that the flat plate material is deformed to align respective positions of end surfaces of the second end portions, a fourth step for curing the flat plate material, and then a fifth step for moving the jig relative to the surface plate to separate from the surface plate the plurality of electronic component bodies in which the respective positions of the end surfaces are aligned.

Abstract: An electronic component manufacturing method comprising: a first step of moving an electronic component body in a first direction relative to a dip layer of a conductive paste to immerse the electronic component body in the dip layer; a second step of moving the electronic component body relative to the dip layer in a second direction that is opposite to the first direction, thereby separating the electronic component body from the dip layer; a third step of forcibly cutting a connection between the conductive paste coated on the end portions of the electronic component body and the dip layer, using a contact with a solid or fluid cutter; and a fourth step of removing excess paste from the conductive paste coated on the end portions of the electronic component body. The third and fourth steps may be conducted simultaneously by cutting and removing the paste with the paste removal member.

Abstract: A method for forming a barium titanate film by conducting an ALD cycle, wherein the ALD cycle comprises forming a titanium oxide film and forming barium oxide film. In the forming of a titanium oxide film, TDMAT (Ti[N(CH3)2]4) is used as first raw material gas, and an OH radical is used as reaction gas, and in the forming of barium oxide film, a vaporized barium complex is used as second raw material gas, and an OH radical is used as reaction gas, and the titanium oxide film and the barium oxide film are alternately formed in a normal order or a reverse order.