Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.

Abstract: A method for calculating a size of a processing unit in a system, the system being configured to perform a reflection process that includes reflecting information on an operation performed in a row-type database on a column-type database in a predetermined processing unit, the method includes: executing a first calculation process for calculating a reference value based on processing costs of multi-version concurrency control performed in the processing unit by the database management system and information on processing costs of a process of converting the information on the operation performed in the row-type database into a form of the column-type database after the reflection process is executed in a previous time; and executing a second calculation process for calculating a size of a processing unit based on the reference value calculated by the first calculation process and information on a deviation of the number of valid rows.

Abstract: A database search apparatus includes a processor that receives a search query including first keys. The processor calculates a first score based on statistical information. The first score represents search performance of searching a first database in accordance with the search query. The first database stores a data group including combinations of a key and a value of the key. The statistical information includes information regarding each key included in the data group. The processor calculates a second score based on the statistical information. The second score represents search performance of searching a second database different from the first database in accordance with the search query, the second database storing the data group. The processor selects the first database or the second database based on the first score and the second score. The processor instructs the selected database to performing a search in accordance with the search query.

Abstract: An update reflection apparatus includes a memory and a processor coupled to the memory. The processor is configured to accumulate first information relating to first records in a write buffer of a row-type. The first records are to update a database of an append-only type. The database is in a column-format. The processor is configured to convert a second record of the first records to a column format. The second record satisfies a specific condition. The processor is configured to append the converted second record to the database.

Abstract: Provided is a battery cell sheet and a secondary battery that can prevent a variation in an electrolyte composition due to volatilization and do not cause a decrease in battery performance even in a case where a component with high volatility is used.

Abstract: A method for calculating a size of a processing unit in a system, the system being configured to perform a reflection process that includes reflecting information on an operation performed in a row-type database on a column-type database in a predetermined processing unit, the method includes: executing a first calculation process for calculating a reference value based on processing costs of multi-version concurrency control performed in the processing unit by the database management system and information on processing costs of a process of converting the information on the operation performed in the row-type database into a form of the column-type database after the reflection process is executed in a previous time; and executing a second calculation process for calculating a size of a processing unit based on the reference value calculated by the first calculation process and information on a deviation of the number of valid rows.

Abstract: A lithium ion secondary battery having a negative electrode includes a negative electrode active material containing at least one of two material of silicon and a silicon compound and carbon, a weight mixing ratio of at least one of two material of the silicon and the silicon compound and the carbon is 20:80 to 50:50, when D90 of particles of at least one of two material of the silicon and the silicon compound is x, D50 of particles of the carbon is y, and the weight mixing ratio of the carbon is z, y??1.17x+0.45z is satisfied, the x is between 2 ?m and 10 ?m, the y is between 10 ?m and 23 ?m, and the z is between 50% and 80% by weight, and a coefficient of expansion when the negative electrode is fully charged is 110% or more and 140% or less.

Abstract: A lithium ion secondary battery that can inhibit an electrolytic solution in the lithium ion secondary battery using a negative electrode active material containing Si from decomposing, improve cycle characteristics, and obtain both a high energy density and a longer service life. A lithium ion secondary battery contains a negative electrode, a positive electrode, a separator installed between the negative and positive electrodes, and an electrolytic solution; the electrolytic solution contains fluoroethylene carbonate; the negative electrode has a negative electrode active material having particles containing silicon and particles containing carbon and a film being formed over a surface of the negative electrode active material and containing fluorine; and a surface area of the particles containing silicon and a content of fluorine contained in the film satisfy the following Formula 1: 0.005 g/m2?(Fluorine content (g) contained in film)/(Surface area (m2) of particles containing silicon)?0.015 g/m2.

Abstract: Provided is a secondary cell excellent in cycle characteristics. The secondary cell includes a positive electrode 5, a negative electrode 6, and an electrolytic solution. A positive electrode mixture of the positive electrode 5 contains LiOH, LiaNibCocAdBeO2 which is a positive electrode active material (a, b, c, d, and e satisfy 1.0?a?1.1, 0.45?b?0.90, 0.05?c+d?0.55, and 0?e?0.006, “A” contains at least one of Mn and Al, and “B” contains at least one of Al, Mg, Mo, Ti, W and Zr), and an oxide. The oxide contains at least one of aluminum oxide, magnesium oxide, molybdenum oxide, titanium oxide, tungsten oxide, and zirconium oxide.

Abstract: Provided are a lithium ion secondary battery that prevents short circuit of a battery in which energy density, cycle characteristics, and safety are all balanced at high levels; and a method for producing the lithium ion secondary battery. The lithium ion secondary battery according to the present invention has a positive electrode, a negative electrode, and a separator provided between the positive electrode and the negative electrode, in which the negative electrode contains a negative electrode active material containing silicon, the hardness of the negative electrode active material is 10 GPa or more and 20 GPa or less, and the separator has a constitution in which a resin layer and a porous layer are laminated, the thickness of the porous layer is 2 ?m or more and 10 ?m or less when the thickness of the resin layer is 25 ?m or more and 30 ?m or less, and the thickness of the porous layer is 5 ?m or more and 20 ?m or less when the thickness of the resin layer is 15 ?m or more but less than 25 ?m.

Abstract: An update reflection apparatus includes a memory and a processor coupled to the memory. The processor is configured to accumulate first information relating to first records in a write buffer of a row-type. The first records are to update a database of an append-only type. The database is in a column-format. The processor is configured to convert a second record of the first records to a column format. The second record satisfies a specific condition. The processor is configured to append the converted second record to the database.

Abstract: Capacity of a lithium ion secondary battery is increased and life of the lithium ion secondary battery is prolonged. A lithium ion secondary battery includes a negative electrode, a positive electrode, and a separator. The negative electrode contains a silicon-containing Si-based negative electrode active material, graphite, and a negative electrode binder.

Abstract: A database search apparatus includes a processor that receives a search query including first keys. The processor calculates a first score based on statistical information. The first score represents search performance of searching a first database in accordance with the search query. The first database stores a data group including combinations of a key and a value of the key. The statistical information includes information regarding each key included in the data group. The processor calculates a second score based on the statistical information. The second score represents search performance of searching a second database different from the first database in accordance with the search query, the second database storing the data group. The processor selects the first database or the second database based on the first score and the second score. The processor instructs the selected database to performing a search in accordance with the search query.

Abstract: A lithium-ion secondary battery of the present invention contains: a laminated electrode group formed of a rectangular positive electrode; a rectangular negative electrode; and a separator. In such a laminated electrode group, the positive electrode includes a positive electrode current collector foil, and a positive electrode mixture layer containing a positive electrode active material, the negative electrode includes a negative electrode current collector foil, and a negative electrode mixture layer containing a negative electrode active material. The negative electrode active material includes a silicon-based material, and a carbonaceous material. A mass ratio of the silicon-based material and the carbonaceous material is 20:80 to 80:20. The silicon-based material is a Si alloy or SiOx (0.5?x?1.5). The positive electrode and the negative electrode have a collection terminal protruding from a same side of the laminated electrode group.

Abstract: A lithium ion secondary battery includes: a positive electrode including a positive electrode active material; a negative electrode formed by coating a negative electrode active material mixture onto a surface of a negative electrode collector, the negative electrode active material mixture including a negative electrode active material, a conductive additive, and a binder; a separator interposed between the positive electrode and the negative electrode; and an electrolyte, in which the negative electrode active material includes graphite and an Si alloy, inequities of 0.43?x?9.0 and 8?y<18 are satisfied when a mass ratio of the graphite and the Si alloy is defined as x and a coating amount of the negative electrode active material mixture is defined as y (mg/cm2). Thus, an initial capacity thereof can be increased and a capacity retention rate thereof can be improved in the lithium ion secondary battery which includes the Si alloy in the negative electrode.

Abstract: A non-transitory computer-readable recording medium stores therein a retrieving control program that causes a computer to execute a process including, receiving a retrieval request including range information; estimating a number of records to be obtained by performing retrieval in a retrieval range; calculating a difference between a cost of retrieval processing time when retrieval processing is performed by a first process or thread which performs the retrieval processing for a record of the total number of records, and the cost of retrieval processing time when retrieval processing is performed by parallel retrieval; calculating a cost of time for giving a record of the estimated number of records from a plurality of processes or threads to the first process or thread; and controlling, according to a comparison result between the difference and the calculated cost of the time, whether the retrieval request is to be processed by the parallel retrieval.

Abstract: A lithium ion secondary battery having a negative electrode includes a negative electrode active material containing at least one of two material of silicon and a silicon compound and carbon, a weight mixing ratio of at least one of two material of the silicon and the silicon compound and the carbon is 20:80 to 50:50, when D90 of particles of at least one of two material of the silicon and the silicon compound is x, D50 of particles of the carbon is y, and the weight mixing ratio of the carbon is z, y??1.17x+0.45z is satisfied, the x is between 2 ?m and 10 ?m, the y is between 10 ?m and 23 ?m, and the z is between 50% and 80% by weight, and a coefficient of expansion when the negative electrode is fully charged is 110% or more and 140% or less.

Abstract: A lithium-ion secondary battery of the present invention contains: a laminated electrode group formed of a rectangular positive electrode; a rectangular negative electrode; and a separator. In such a laminated electrode group, the positive electrode includes a positive electrode current collector foil, and a positive electrode mixture layer containing a positive electrode active material, the negative electrode includes a negative electrode current collector foil, and a negative electrode mixture layer containing a negative electrode active material. The negative electrode active material includes a silicon-based material, and a carbonaceous material. A mass ratio of the silicon-based material and the carbonaceous material is 20:80 to 80:20. The silicon-based material is a Si alloy or SiOx (0.5?x?1.5). The positive electrode and the negative electrode have a collection terminal protruding from a same side of the laminated electrode group.

Abstract: A lithium ion secondary battery includes: a positive electrode including a positive electrode active material; a negative electrode formed by coating a negative electrode active material mixture onto a surface of a negative electrode collector, the negative electrode active material mixture including a negative electrode active material, a conductive additive, and a binder; a separator interposed between the positive electrode and the negative electrode; and an electrolyte, in which the negative electrode active material includes graphite and an Si alloy, inequities of 0.43?x?9.0 and 8?y<18 are satisfied when a mass ratio of the graphite and the Si alloy is defined as x and a coating amount of the negative electrode active material mixture is defined as y (mg/cm2). Thus, an initial capacity thereof can be increased and a capacity retention rate thereof can be improved in the lithium ion secondary battery which includes the Si alloy in the negative electrode.

Abstract: In manufacturing a negative electrode for a lithium-ion secondary battery, the negative electrode including a negative-electrode mixture layer including a negative-electrode active material and a binder containing at least one selected from a group consisting of a polyimide, a polyamide-imide and a polyamide, and a negative-electrode collector, the negative-electrode collector coated with a negative-electrode mixture slurry containing the binder is pressed by a hot-press roller which is heated to perform thermal curing and press together, such that the negative-electrode collector with the negative-electrode mixture slurry has a temperature of 200 to 400° C.