Patents by Inventor Eike Hoffman

Eike Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Incretin Receptor Ligand Polypeptide Fc-Region Fusion Polypeptides And Conjugates With Altered Fc-Effector Function
    Publication number: 20140051834
    Abstract: Herein is reported an Fc-region fusion polypeptide or Fc-region conjugate comprising one to four incretin receptor ligand polypeptides and a variant human Fc-region with a mutation of the amino acid residue at position 329 and at least one further mutation of at least one amino acid selected from the group comprising amino acid residues at position 228, 233, 234, 235, 236, 237, 297, 318, 320, 322 and 331 to a different residue, wherein the residues in the Fc-region are numbered according to the EU index of Kabat and its use as a medicament.
    Type: Application
    Filed: June 18, 2013
    Publication date: February 20, 2014
    Applicants: Hoffmann-La Roche, Inc., Indiana University Research and Technology Corporation
    Inventors: Eike HOFFMAN, Erhard KOPETZKI, Matthias RUETH, Georg TIEFENTHALER, Richard D. DiMARCHI
  • BI-SPECIFIC DIGOXIGENIN BINDING ANTIBODIES
    Publication number: 20120282280
    Abstract: This invention relates to bispecific antibodies and antibody fragments against a target protein and a hapten, wherein the hapten is PEG or biotin, most preferably digoxigenin, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical 5 compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: June 30, 2010
    Publication date: November 8, 2012
    Inventors: Birgit Bramlage, Ulrich Brinkmann, Rebecca Croasdale, Simone Dill, Wilma Dormeyer, Guy Georges, Michael Grote, Alexander Haas, Eike Hoffman, Ludger Markus Ickenstein, Kerstin Jahn-Hofman, Matthias John, Silke Metz, Olaf Mundigl, Werner Scheuer, Jan Olaf Stracke
  • COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT
    Publication number: 20120269723
    Abstract: The present invention relates to complexes of a) bi-specific antibodies and antibody fragments against a target protein and b) a digoxigenin conjugated to a therapeutic or diagnostic agent, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: July 5, 2010
    Publication date: October 25, 2012
    Inventors: Ulrich Brinkmann, Rebecca Croasdale, Wilma Dormeyer, Guy Georges, Alexander Haas, Eike Hoffman, Silke Metz, Olaf Mundigl, Werner Scheuer, Jan Olaf Stracke