Patent number: 7276633
Abstract: The present invention relates to a process for the preparation of a compound of the general formula R-(A1-Z-)mB—CF2O-A2-(A3)n—R???(I) in which R is alkyl, in which one or more CH2 groups may be replaced, independently of one another, by O, CF2, CH?CH, CH?CF or CF?CF, with the proviso that peroxide structures O—O and formaldehyde acetals O—CH2—O are excluded, A1 is, independently of one another, 1,4-cyclohexylene, 2,5-1,3-dioxanylene, 1,3-cyclobutylene or A2 and A3 are 1,4-phenylene, in which, independently of one another, from one to four hydrogens may be replaced by fluorine or one or two CH groups may be replaced by N, Z is a single bond, —CH2—CH2—, —CF2—CF2—, —CH?CH—, —CF?CF—, —CH?CF— or —CF?CH—, B is 2,6-disubstituted naphthalene, 2,6-disubstituted 5,6,7,8-tetrahydronaphthalene or 2,6-disubstituted trans-decalin, R? is R, F, OCF3, OCF2H, CF3, CI, SF5, CN or NCS, and m and n are, independently of one another, 0 or 1, comprising the following steps: a) conversion of a compound of the genera
Type:
Grant
Filed:
October 30, 2003
Date of Patent:
October 2, 2007
Assignee:
Merck Patent GmbH
Inventors:
Eike Poetsch, Werner Binder, Peer Kirsch, Andreas Taugerbeck