Patents by Inventor Eiko Kato

Eiko Kato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11045471
    Abstract: The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: June 29, 2021
    Assignee: SHOWA DENKO K.K.
    Inventors: Daisuke Yagyu, Yuko Nakagami, Ryota Niibayashi, Eiko Kato
  • Patent number: 10876974
    Abstract: An inspection device (1) inspects an amount of dielectric particles contained in a sample liquid. The inspection device includes a dielectric collection unit (3), a pump unit (10) and an AC voltage supply unit (11). The dielectric collection unit includes at least one pair of electrodes (41, 42) and a flow channel (13) extending in a predetermined direction on the pair of electrodes. The pump unit is configured to feed the sample liquid to follow the flow channel in the predetermined direction. The AC voltage supply unit is configured to supply, to the pair of electrodes, an AC voltage with a predetermined frequency to cause dielectrophoresis for dielectric particles in the fed sample liquid. The dielectric collection unit includes a plurality of slit regions (Rs) aligned in the predetermined direction between the pair of electrodes. Each of the plurality of slit regions is separated from each other within the flow channel.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: December 29, 2020
    Assignee: AFI CORPORATION
    Inventors: Takaharu Enjoji, Yoshikazu Wakizaka, Satoshi Uchida, Eiko Kato, Masayo Takano
  • Publication number: 20200215069
    Abstract: The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring.
    Type: Application
    Filed: March 17, 2020
    Publication date: July 9, 2020
    Applicant: SHOWA DENKO K.K.
    Inventors: Daisuke YAGYU, Yuko NAKAGAMI, Ryota NIIBAYASHI, Eiko KATO
  • Patent number: 10646487
    Abstract: The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring].
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: May 12, 2020
    Assignee: SHOWA DENKO K.K.
    Inventors: Daisuke Yagyu, Yuko Nakagami, Ryota Niibayashi, Eiko Kato
  • Publication number: 20200064274
    Abstract: An inspection device (1) inspects an amount of dielectric particles contained in a sample liquid. The inspection device includes a dielectric collection unit (3), a pump unit (10) and an AC voltage supply unit (11). The dielectric collection unit includes at least one pair of electrodes (41, 42) and a flow channel (13) extending in a predetermined direction on the pair of electrodes. The pump unit is configured to feed the sample liquid to follow the flow channel in the predetermined direction. The AC voltage supply unit is configured to supply, to the pair of electrodes, an AC voltage with a predetermined frequency to cause dielectrophoresis for dielectric particles in the fed sample liquid. The dielectric collection unit includes a plurality of slit regions (Rs) aligned in the predetermined direction between the pair of electrodes. Each of the plurality of slit regions is separated from each other within the flow channel.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 27, 2020
    Inventors: Takaharu ENJOJI, Yoshikazu WAKIZAKA, Satoshi UCHIDA, Eiko KATO, Masayo TAKANO
  • Patent number: 10495580
    Abstract: An inspection device (1) inspects an amount of dielectric particles contained in a sample liquid. The inspection device includes a dielectric collection unit (3), a pump unit (10) and an AC voltage supply unit (11). The dielectric collection unit includes at least one pair of electrodes (41, 42) and a flow channel (13) extending in a predetermined direction on the pair of electrodes. The pump unit is configured to feed the sample liquid to follow the flow channel in the predetermined direction. The AC voltage supply unit is configured to supply, to the pair of electrodes, an AC voltage with a predetermined frequency to cause dielectrophoresis for dielectric particles in the fed sample liquid. The dielectric collection unit includes a plurality of slit regions (Rs) aligned in the predetermined direction between the pair of electrodes. Each of the plurality of slit regions is separated from each other within the flow channel.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: December 3, 2019
    Assignee: AFI Corporation
    Inventors: Takaharu Enjoji, Yoshikazu Wakizaka, Satoshi Uchida, Eiko Kato, Masayo Takano
  • Publication number: 20190224199
    Abstract: The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring.
    Type: Application
    Filed: June 8, 2017
    Publication date: July 25, 2019
    Applicant: SHOWA DENKO K.K.
    Inventors: Daisuke YAGYU, Yuko NAKAGAMI, Ryota NIIBAYASHI, Eiko KATO
  • Publication number: 20180149601
    Abstract: An inspection device (1) inspects an amount of dielectric particles contained in a sample liquid. The inspection device includes a dielectric collection unit (3), a pump unit (10) and an AC voltage supply unit (11). The dielectric collection unit includes at least one pair of electrodes (41, 42) and a flow channel (13) extending in a predetermined direction on the pair of electrodes. The pump unit is configured to feed the sample liquid to follow the flow channel in the predetermined direction. The AC voltage supply unit is configured to supply, to the pair of electrodes, an AC voltage with a predetermined frequency to cause dielectrophoresis for dielectric particles in the fed sample liquid. The dielectric collection unit includes a plurality of slit regions (Rs) aligned in the predetermined direction between the pair of electrodes. Each of the plurality of slit regions is separated from each other within the flow channel.
    Type: Application
    Filed: October 5, 2016
    Publication date: May 31, 2018
    Inventors: Takaharu ENJOJI, Yoshikazu WAKIZAKA, Satoshi UCHIDA, Eiko KATO, Masayo TAKANO
  • Publication number: 20180086779
    Abstract: A tocopherol phosphoric acid ester salt in which the tocopherol phosphoric acid ester salt is represented by Formula (1), and in the Formula (1), “R1”, “R2”, and “R3” each independently represents a hydrogen atom or a methyl group, “M” represents an alkali metal, and “a” is 1.10 or more and 2.00 or less.
    Type: Application
    Filed: May 20, 2016
    Publication date: March 29, 2018
    Applicant: SHOWA DENKO K.K.
    Inventors: Eiko KATO, Hiroshi ISHII, Akira SHIBUYA
  • Publication number: 20170312301
    Abstract: The present invention provides a skin barrier function-improving agent including an inositol derivative as an active ingredient in which inositol and saccharide are bonded, and a composition for improving a skin barrier function including the above skin barrier function-improving agent and a pharmacologically acceptable carrier.
    Type: Application
    Filed: July 23, 2015
    Publication date: November 2, 2017
    Applicant: SHOWA DENKO K.K.
    Inventors: Yuko SAEKI, Eiko KATO
  • Publication number: 20170312207
    Abstract: The present invention provides a moisturizing agent including an inositol derivative as an active ingredient in which saccharide of three or more monosaccharide unit is bonded to per molecule of inositol.
    Type: Application
    Filed: November 10, 2015
    Publication date: November 2, 2017
    Applicant: SHOWA DENKO K.K.
    Inventors: Yuko SAEKI, Eiko KATO
  • Patent number: 8278350
    Abstract: An agent for skin external use of the invention contains a salt of higher fatty acid ester of ascorbic acid-2-phosphoric acid ester and a polyhydric alcohol. According to the present invention, occurrence of turbidity or precipitation with time can be prevented to enhance stability even when the agent for skin external use is prepared using a specific salt of higher fatty acid ester of ascorbic acid-2-phosphoric acid ester. Therefore, the present invention is useful for all agents for skin external use, particularly cosmetics.
    Type: Grant
    Filed: October 13, 2004
    Date of Patent: October 2, 2012
    Assignee: Showa Denko K.K.
    Inventors: Eiko Kato, Tadashi Yoneda, Eiji Ogata
  • Publication number: 20110144062
    Abstract: A dermatological anti-wrinkle agent and an anti-wrinkle cosmetic are stable and satisfactorily effective against wrinkles. The dermatological anti-wrinkle agent includes a tocopherol phosphate represented by the following formula (1): and/or a salt thereof, wherein R1, R2, and R3 represent a hydrogen atom or a methyl group. The anti-wrinkle cosmetic includes the anti-wrinkle agent.
    Type: Application
    Filed: February 23, 2011
    Publication date: June 16, 2011
    Applicant: SHOWA DENKO K.K.
    Inventors: Eiko KATO, Toshi TSUZUKI
  • Publication number: 20090203649
    Abstract: A dermatological anti-wrinkle agent and an anti-wrinkle cosmetic are stable and satisfactorily effective against wrinkles. The dermatological anti-wrinkle agent comprises a tocopherol phosphate represented by the following formula (1): and/or a salt thereof, wherein R1, R2, and R3 represent a hydrogen atom or a methyl group. The anti-wrinkle cosmetic includes the anti-wrinkle agent.
    Type: Application
    Filed: June 25, 2007
    Publication date: August 13, 2009
    Applicant: SHOWA DENKO K.K.
    Inventors: Eiko Kato, Toshi Tsuzuki
  • Publication number: 20070232698
    Abstract: The invention provides a slimming skin external preparation and a cosmetic that contain a carnitine derivative having excellent skin affinity and percutaneous absorption properties and capable of enhancing the fat metabolism, and that can treat, reduce or prevent the obesity by functioning as a lipolytic agent to enhance the fat metabolism of general or local subcutaneous fat tissues. The slimming skin external preparation contains a particular carnitine derivative and preferably other slimming and skin-care ingredients.
    Type: Application
    Filed: May 31, 2005
    Publication date: October 4, 2007
    Inventors: Akira Shibuya, Eiko Kato, Motoaki Kamachi, Hirobumi Aoki
  • Publication number: 20070232687
    Abstract: The agent for skin external use of the present invention contains (A) tocopherol glycine esters, (B) ascorbic acid-2-phosphoric acid esters and a specific amount of (C) an anionic surface active agent having a lipopeptide structure. According to the agent for skin external use (including a cosmetic) of the present invention, it is possible to enhance stability of the tocopherol glycine esters in spite that the tocopherol glycine esters and the ascorbic acids are contained simultaneously, so that occurrence of coloring (including turbidity) and/or precipitation with time can be prevented. Therefore, efficacy and effects of the agent or the cosmetic can be well exerted over a long period of time.
    Type: Application
    Filed: April 19, 2005
    Publication date: October 4, 2007
    Inventors: Eiko Kato, Toshi Tsuzuki, Eiji Ogata
  • Publication number: 20070140998
    Abstract: An agent for skin external use of the invention contains a salt of higher fatty acid ester of ascorbic acid-2-phosphoric acid ester and a polyhydric alcohol. According to the present invention, occurrence of turbidity or precipitation with time can be prevented to enhance stability even when the agent for skin external use is prepared using a specific salt of higher fatty acid ester of ascorbic acid-2-phosphoric acid ester. Therefore, the present invention is useful for all agents for skin external use, particularly cosmetics.
    Type: Application
    Filed: October 13, 2004
    Publication date: June 21, 2007
    Applicant: SHOWA DENKO K.K.
    Inventors: Eiko Kato, Tadashi Yoneda, Eiji Ogata
  • Publication number: 20050220733
    Abstract: The invention relates to skin whitening external preparations which contain tocopherol phosphate and/or a salt thereof as an active ingredient capable of prevention and/or removal of skin pigmentation, cosmetics including the skin whitening external preparation and cosmetic cares using the cosmetic. The skin whitening external preparations have excellent skin whitening effects and are readily producible so that they can find wide use for the purpose of skin whitening.
    Type: Application
    Filed: May 7, 2003
    Publication date: October 6, 2005
    Applicant: SHOWA DENKO K.K.
    Inventors: Toshi Tsuzuki, Eiko Kato, Eiji Ogata, Hiroshi Ikeno
  • Publication number: 20050208002
    Abstract: A preparation for external use on skin which comprises an active ingredient exhibiting superior effects of preventing pigmentation or eliminating pigments formed in the skin, and has a high level of safety, and in particular, a cosmetic composition exhibiting superior so-called whitening effects, are provided. The whitening cosmetic composition comprises a tocopherol alkylglycine ester and/or a salt thereof.
    Type: Application
    Filed: March 6, 2003
    Publication date: September 22, 2005
    Inventors: Eiko Kato, Eiji Ogata, Tadashi Yoneda, Jiro Takata
  • Publication number: 20050065206
    Abstract: The present invention relates to a skin preparation for external application, comprising a tocopherol aminoalkylcarboxylate ester having no substituent on the N atom and/or a salt thereof. Preferable tocopherol aminoalkylcarboxylate in the present invention is one or more compound selected from ?-tocopherol derivatives, ?-tocopherol derivatives, ?-tocopherol derivatives and ?-tocopherol derivatives. The present invention also relates to a cosmetic material comprising the skin preparation.
    Type: Application
    Filed: October 28, 2002
    Publication date: March 24, 2005
    Inventors: Eiko Kato, Toshi Tsuzuki, Jiro Takata, Yoshiharu Karube, Kazuhisa Matsunaga, Shizuko Kobayashi