Patents by Inventor Eileen Denovan-Wright

Eileen Denovan-Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for modulating phosphodiesterase 10A
    Publication number: 20070060606
    Abstract: Novel compounds that modulate PDE10A, a gene that is primarily expressed in medium spiny neurons of the mammalian striatum and has been found to inhibit striatal output by reducing spiny medium excitability and effect cAMP and cGMP signalling cascades in vivo in rats, and methods for treating psychosis and schizophrenia using the novel compounds. Methods for screening for further compounds to modulate PDE10A activity are also taught.
    Type: Application
    Filed: August 23, 2006
    Publication date: March 15, 2007
    Inventors: Harold Robertson, Eileen Denovan-Wright, Donald Weaver