Patents by Inventor Eileen Friedman

Eileen Friedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for growth in tissue culture of normal colonic epithelial cells and method for determination of preneoplastic color cells
    Patent number: 4743552
    Abstract: The invention concerns a method for the routine primary culture of human colonic epithelial cells within a monolayer. 12-0-tetradecanoylphorbol-13-acetate (TPA) enhanced DNA synthesis an average of 8 fold when assayed by [.sup.3 h]dThd labeling indices (L.I.) in colonic epithelial cells from familial polyposis patients and in tubular adenomas. No such stimulation by TPA was seen in cells from high-risk patients without familial polyposis, or in cells from low-risk subjects.
    Type: Grant
    Filed: September 26, 1984
    Date of Patent: May 10, 1988
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Eileen A. Friedman, Martin Lipkin
  • Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies
    Patent number: 4579827
    Abstract: A panel of monoclonal antibodies produced from human gastrointestinal tumors as immunogen is used to diagnose the presence of colon cancer. The antibody panel subsets the human gastrointestinal tract in its reactivity vis-a-vis esophagus, stomach, small intestine and colon. The panel is useful as a diagnostic probe for cancer.
    Type: Grant
    Filed: March 11, 1983
    Date of Patent: April 1, 1986
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Junichi Sakamoto, Carlos Cordon-Cardo, Eileen Friedman, Connie L. Finstad, Warren E. Enker, Myron R. Melamed, Kenneth O. Lloyd, Herbert F. Oettgen, Lloyd J. Old