Patents by Inventor Eileen Ingham

Eileen Ingham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9951103
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: April 24, 2018
    Assignee: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9937265
    Abstract: Novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefore are described. The novel self-assembling peptide complexes have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. Methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth are also described.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: April 10, 2018
    Assignee: University of Leeds
    Inventors: Eileen Ingham, Ruth Karen Wilcox, Amalia Aggeli, Danielle Elizabeth Miles
  • Patent number: 9901450
    Abstract: The invention provides natural multi-composite bone implants such as bone-connective tissue-bone and osteochondral implants for the replacement and/or repair of, for example and in particular a damaged or defective bone-meniscus-bone joint or a bone-patella tendon-bone joint or osteochondral lesions, methods of preparing the composites and uses thereof. The invention also provides natural or native composite bone-connective tissue-bone and osteochondral matrices or scaffolds that are substantially decellularized for subsequent transplantation/implantation.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: February 27, 2018
    Assignee: University of Leeds
    Inventors: Eileen Ingham, Gemma Jones, Hazel Fermor, John Fisher, Jahid Hasan
  • Publication number: 20170232145
    Abstract: The invention provides natural multi-composite bone implants such as bone-connective tissue-bone and osteochondral implants for the replacement and/or repair of, for example and in particular a damaged or defective bone-meniscus-bone joint or a bone-patella tendon-bone joint or osteochondral lesions, methods of preparing the composites and uses thereof. The invention also provides natural or native composite bone-connective tissue-bone and osteochondral matrices or scaffolds that are substantially decellularised for subsequent transplantation/implantation.
    Type: Application
    Filed: May 1, 2017
    Publication date: August 17, 2017
    Inventors: Eileen Ingham, Gemma Jones, Hazel Fermor, John Fisher, Jahid Hasan
  • Publication number: 20170190740
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.
    Type: Application
    Filed: March 16, 2017
    Publication date: July 6, 2017
    Applicant: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9663555
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: May 30, 2017
    Assignee: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9630991
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: April 25, 2017
    Assignee: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9510933
    Abstract: A product comprising a natural acellular xenogenic vascular tissue matrix having at least an 80% reduction in DNA content as compared to an untreated control vascular tissue matrix and being antigenically inert by being substantially free of epitopes capable of reacting with pre-formed human antibodies and also without having the ability to substantially activate complement. The invention also includes methods of preparing such products and uses of the products especially in bypass surgery.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: December 6, 2016
    Assignee: Tissue Regenix Limited
    Inventors: Eileen Ingham, John Fisher, Stacy-Paul Wilshaw
  • Publication number: 20160340392
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.
    Type: Application
    Filed: August 11, 2016
    Publication date: November 24, 2016
    Applicant: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9447151
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: September 20, 2016
    Assignee: The University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Publication number: 20160185824
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.
    Type: Application
    Filed: March 10, 2016
    Publication date: June 30, 2016
    Applicant: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9315550
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: April 19, 2016
    Assignee: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Publication number: 20160058871
    Abstract: The invention relates to novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefor. The novel self-assembling peptide complexes of the present invention have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. The invention provides inter alia methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth.
    Type: Application
    Filed: April 8, 2014
    Publication date: March 3, 2016
    Applicant: University of Leeds
    Inventors: Eileen Ingham, Ruth Karen Wilcox, Amalia Aggeli, Danielle Elizabeth Miles
  • Publication number: 20160046670
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.
    Type: Application
    Filed: October 20, 2015
    Publication date: February 18, 2016
    Applicant: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9193764
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: November 24, 2015
    Assignee: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9187527
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: November 17, 2015
    Assignee: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9180143
    Abstract: The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularization is carried out on an expanded or distended bladder and the product retains the strength and compliance of natural material. The invention also provides use of the matrix scaffolds as wound healing material and to investigate tissue structure and function in vitro.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: November 10, 2015
    Assignee: Tissue Regenix Limited
    Inventors: Fiona Bolland, Jennifer Southgate, Sotirios Korossis, Eileen Ingham
  • Patent number: 9180144
    Abstract: The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularisation is carried out on an expanded or distended bladder and the product retains the strength and compliance of natural material. The invention also provides use of the matrix scaffolds as wound healing material and to investigate tissue structure and function in vitro.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: November 10, 2015
    Assignee: Tissue Regenix Limited
    Inventors: Fiona Bolland, Jennifer Southgate, Sotirios Korossis, Eileen Ingham
  • Publication number: 20150299266
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.
    Type: Application
    Filed: July 6, 2015
    Publication date: October 22, 2015
    Applicant: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
  • Patent number: 9101687
    Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: August 11, 2015
    Assignee: University of Leeds
    Inventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham