Patents by Inventor Eileen Ingham
Eileen Ingham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9951103Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.Type: GrantFiled: March 16, 2017Date of Patent: April 24, 2018Assignee: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9937265Abstract: Novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefore are described. The novel self-assembling peptide complexes have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. Methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth are also described.Type: GrantFiled: April 8, 2014Date of Patent: April 10, 2018Assignee: University of LeedsInventors: Eileen Ingham, Ruth Karen Wilcox, Amalia Aggeli, Danielle Elizabeth Miles
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Patent number: 9901450Abstract: The invention provides natural multi-composite bone implants such as bone-connective tissue-bone and osteochondral implants for the replacement and/or repair of, for example and in particular a damaged or defective bone-meniscus-bone joint or a bone-patella tendon-bone joint or osteochondral lesions, methods of preparing the composites and uses thereof. The invention also provides natural or native composite bone-connective tissue-bone and osteochondral matrices or scaffolds that are substantially decellularized for subsequent transplantation/implantation.Type: GrantFiled: September 4, 2013Date of Patent: February 27, 2018Assignee: University of LeedsInventors: Eileen Ingham, Gemma Jones, Hazel Fermor, John Fisher, Jahid Hasan
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Publication number: 20170232145Abstract: The invention provides natural multi-composite bone implants such as bone-connective tissue-bone and osteochondral implants for the replacement and/or repair of, for example and in particular a damaged or defective bone-meniscus-bone joint or a bone-patella tendon-bone joint or osteochondral lesions, methods of preparing the composites and uses thereof. The invention also provides natural or native composite bone-connective tissue-bone and osteochondral matrices or scaffolds that are substantially decellularised for subsequent transplantation/implantation.Type: ApplicationFiled: May 1, 2017Publication date: August 17, 2017Inventors: Eileen Ingham, Gemma Jones, Hazel Fermor, John Fisher, Jahid Hasan
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Publication number: 20170190740Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.Type: ApplicationFiled: March 16, 2017Publication date: July 6, 2017Applicant: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9663555Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.Type: GrantFiled: August 11, 2016Date of Patent: May 30, 2017Assignee: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9630991Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.Type: GrantFiled: October 20, 2015Date of Patent: April 25, 2017Assignee: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9510933Abstract: A product comprising a natural acellular xenogenic vascular tissue matrix having at least an 80% reduction in DNA content as compared to an untreated control vascular tissue matrix and being antigenically inert by being substantially free of epitopes capable of reacting with pre-formed human antibodies and also without having the ability to substantially activate complement. The invention also includes methods of preparing such products and uses of the products especially in bypass surgery.Type: GrantFiled: September 26, 2011Date of Patent: December 6, 2016Assignee: Tissue Regenix LimitedInventors: Eileen Ingham, John Fisher, Stacy-Paul Wilshaw
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Publication number: 20160340392Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.Type: ApplicationFiled: August 11, 2016Publication date: November 24, 2016Applicant: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9447151Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.Type: GrantFiled: March 10, 2016Date of Patent: September 20, 2016Assignee: The University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Publication number: 20160185824Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.Type: ApplicationFiled: March 10, 2016Publication date: June 30, 2016Applicant: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9315550Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.Type: GrantFiled: July 6, 2015Date of Patent: April 19, 2016Assignee: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Publication number: 20160058871Abstract: The invention relates to novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefor. The novel self-assembling peptide complexes of the present invention have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. The invention provides inter alia methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth.Type: ApplicationFiled: April 8, 2014Publication date: March 3, 2016Applicant: University of LeedsInventors: Eileen Ingham, Ruth Karen Wilcox, Amalia Aggeli, Danielle Elizabeth Miles
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Publication number: 20160046670Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.Type: ApplicationFiled: October 20, 2015Publication date: February 18, 2016Applicant: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9193764Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.Type: GrantFiled: October 24, 2013Date of Patent: November 24, 2015Assignee: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9187527Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.Type: GrantFiled: March 3, 2014Date of Patent: November 17, 2015Assignee: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9180144Abstract: The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularisation is carried out on an expanded or distended bladder and the product retains the strength and compliance of natural material. The invention also provides use of the matrix scaffolds as wound healing material and to investigate tissue structure and function in vitro.Type: GrantFiled: July 29, 2014Date of Patent: November 10, 2015Assignee: Tissue Regenix LimitedInventors: Fiona Bolland, Jennifer Southgate, Sotirios Korossis, Eileen Ingham
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Patent number: 9180143Abstract: The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularization is carried out on an expanded or distended bladder and the product retains the strength and compliance of natural material. The invention also provides use of the matrix scaffolds as wound healing material and to investigate tissue structure and function in vitro.Type: GrantFiled: July 29, 2014Date of Patent: November 10, 2015Assignee: Tissue Regenix LimitedInventors: Fiona Bolland, Jennifer Southgate, Sotirios Korossis, Eileen Ingham
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Publication number: 20150299266Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.Type: ApplicationFiled: July 6, 2015Publication date: October 22, 2015Applicant: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham
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Patent number: 9101687Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.Type: GrantFiled: July 18, 2012Date of Patent: August 11, 2015Assignee: University of LeedsInventors: Neville Boden, Amalia Aggeli, Eileen Ingham, Jennifer Kirkham