Patents by Inventor Eing-Mei Tsai

Eing-Mei Tsai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220267724
    Abstract: Provided herein are isolated neural stem cells and methods of making neural stem cells from human trophoblast stem cells. The isolated neural stem cells can be immune privileged and express one or more protein(s). Also provided are methods for treatment of neurodegenerative diseases using suitable preparations comprising the isolated neural stem cells.
    Type: Application
    Filed: November 22, 2021
    Publication date: August 25, 2022
    Inventors: Jau-Nan LEE, Tony Tung-Ying LEE, Yuta LEE, Eing-Mei TSAI
  • Patent number: 11254911
    Abstract: Provided herein are isolated neural stem cells. Also provided are methods for treatment of neurodegenerative diseases using suitable preparations comprising the isolated neural stem cells.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: February 22, 2022
    Assignee: ACCELERATED BIOSCIENCES CORP.
    Inventors: Jau-Nan Lee, Tony Tung-Ying Lee, Yuta Lee, Eing-Mei Tsai
  • Publication number: 20210330713
    Abstract: Disclosed herein are human hepatocytes for example isolated human hepatic progenitor cells, artificial tissue or organ thereof, and kits or compositions thereof. Also disclosed herein are various methods of using a human hepatocyte disclosed herein.
    Type: Application
    Filed: April 29, 2021
    Publication date: October 28, 2021
    Inventors: Jau-Nan LEE, Tony Tung-Yin LEE, Yuta LEE, Eing-Mei TSAI
  • Patent number: 11026979
    Abstract: Disclosed herein are human hepatocytes for example isolated human hepatic progenitor cells, artificial tissue or organ thereof, and kits or compositions thereof. Also disclosed herein are various methods of using a human hepatocyte disclosed herein.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: June 8, 2021
    Assignee: ACCELERATED BIOSCIENCES CORP.
    Inventors: Jau-Nan Lee, Tony Tung-Yin Lee, Yuta Lee, Eing-Mei Tsai
  • Publication number: 20200345788
    Abstract: Disclosed herein are human hepatocytes for example isolated human hepatic progenitor cells, artificial tissue or organ thereof, and kits or compositions thereof. Also disclosed herein are various methods of using a human hepatocyte disclosed herein.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 5, 2020
    Inventors: Jau-Nan LEE, Tony Tung-Yin LEE, Yuta LEE, Eing-Mei TSAI
  • Patent number: 10765704
    Abstract: Disclosed herein are induced hepatocytes from a trophoblast stem cell, methods for inducing the cells, and compositions thereof. Also disclosed herein are methods of treating a disease or disorder (e.g., liver-associated) by utilizing an induced hepatocyte disclosed herein.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: September 8, 2020
    Assignee: ACCELERATED BIOSCIENCES CORP.
    Inventors: Jau-Nan Lee, Tony Tung-Yin Lee, Yuta Lee, Eing-Mei Tsai
  • Publication number: 20180000868
    Abstract: Disclosed herein are induced hepatocytes from a trophoblast stem cell, methods for inducing the cells, and compositions thereof. Also disclosed herein are methods of treating a disease or disorder (e.g., liver-associated) by utilizing an induced hepatocyte disclosed herein.
    Type: Application
    Filed: September 15, 2017
    Publication date: January 4, 2018
    Inventors: Jau-Nan LEE, Tony Tung-Yin LEE, Yuta LEE, Eing-Mei TSAI
  • Publication number: 20170349955
    Abstract: A method for predicting a survival rate of a breast cancer patient, including: providing a biological sample of the breast cancer patient; measuring miR-125a-5p expression level in the biological sample; and comparing the miR-125a-5p expression level in the biological sample of the breast cancer patient with miR-125a-5p expression level in another biological sample of a reference breast cancer patient. When the miR-125a-5p expression level in the biological sample of the breast cancer patient is lower than that of the reference breast cancer patient, the survival rate of the breast cancer patient is lower than that of the reference breast cancer patient. When the miR-125a-5p expression level in the biological sample of the breast cancer patient is greater than that of the reference breast cancer patient, the survival rate of the breast cancer patient is greater than that of the reference breast cancer patient.
    Type: Application
    Filed: August 21, 2017
    Publication date: December 7, 2017
    Inventors: Eing-Mei TSAI, Tsung-Hua HSIEH
  • Patent number: 9808490
    Abstract: Disclosed herein are induced hepatocytes from a trophoblast stem cell, methods for inducing the cells, and compositions thereof. Also disclosed herein are methods of treating a disease or disorder (e.g., liver-associated) by utilizing an induced hepatocyte disclosed herein.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: November 7, 2017
    Assignee: ACCELERATED BIOSCIENCES CORP.
    Inventors: Jau-Nan Lee, Tony Tung-Yin Lee, Yuta Lee, Eing-Mei Tsai
  • Publication number: 20170159014
    Abstract: Provided herein are isolated neural stem cells. Also provided are methods for treatment of neurodegenerative diseases using suitable preparations comprising the isolated neural stem cells.
    Type: Application
    Filed: November 29, 2016
    Publication date: June 8, 2017
    Inventors: Jau-Nan LEE, Tony Tung-Ying LEE, Yuta LEE, Eing-Mei TSAI
  • Publication number: 20170145421
    Abstract: The present invention relates to a method for predicting a survival rate of a breast cancer patient, comprising: providing a biological sample of the breast cancer patient; measuring miR-125a-5p expression level in the biological sample; and comparing the miR-125a-5p expression level in the biological sample of the breast cancer patient with miR-125a-5p expression level in another biological sample of a reference breast cancer patient; wherein when the miR-125a-5p expression level in the biological sample of the breast cancer patient is lower than that of the reference breast cancer patient, the survival rate of the breast cancer patient is lower than that of the reference breast cancer patient; or when the miR-125a-5p expression level in the biological sample of the breast cancer patient is greater than that of the reference breast cancer patient, the survival rate of the breast cancer patient is greater than that of the reference breast cancer patient.
    Type: Application
    Filed: November 17, 2016
    Publication date: May 25, 2017
    Inventors: Eing-Mei TSAI, Tsung-Hua Hsieh
  • Patent number: 9574173
    Abstract: Provided herein are isolated neural stem cells. Also provided are methods for treatment of neurodegenerative diseases using suitable preparations comprising the isolated neural stem cells.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: February 21, 2017
    Assignee: ACCELERATED BIOSCIENCES CORP.
    Inventors: Jau-Nan Lee, Tony Tung-Ying Lee, Yuta Lee, Eing-Mei Tsai
  • Publication number: 20160199416
    Abstract: Disclosed herein are induced hepatocytes from a trophoblast stem cell, methods for inducing the cells, and compositions thereof. Also disclosed herein are methods of treating a disease or disorder (e.g., liver-associated) by utilizing an induced hepatocyte disclosed herein.
    Type: Application
    Filed: November 25, 2015
    Publication date: July 14, 2016
    Inventors: Jau-Nan LEE, Tony Tung-Yin LEE, Yuta LEE, Eing-Mei TSAI
  • Patent number: 9322017
    Abstract: The invention discloses a diagnosis of endometriosis, by determining a level of miR-199a-5p as a biomarker to diagnose endometriosis. The invention also discloses a treatment of endometriosis, by administering pre-miR-199a to a subject in need thereof in a dosage of 4 to 8 mg/per kilogram of body weight per 1 to 3 days for 4 weeks to inhibit the processes of endometriosis development.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: April 26, 2016
    Assignee: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Eing-Mei Tsai, Chia-Yi Hsu
  • Publication number: 20150291959
    Abstract: The invention discloses a diagnosis of endometriosis, by determining a level of miR-199a-5p as a biomarker to diagnose endometriosis. The invention also discloses a treatment of endometriosis.
    Type: Application
    Filed: September 11, 2014
    Publication date: October 15, 2015
    Inventors: Eing-Mei TSAI, Chia-Yi HSU
  • Publication number: 20120135878
    Abstract: Provided herein are isolated neural stem cells. Also provided are methods for treatment of neurodegenerative diseases using suitable preparations comprising the isolated neural stem cells.
    Type: Application
    Filed: November 15, 2011
    Publication date: May 31, 2012
    Inventors: Jau-Nan LEE, Tony Tung-Ying Lee, Yuta Lee, Eing-Mei Tsai