Patents by Inventor Eirini Antonatou

Eirini Antonatou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOCONJUGATION REAGENT AND METHODS
    Publication number: 20220169604
    Abstract: The present invention in general relates to the field of bioconjugation. More in particular, the invention relates to novel bioconjugation reactants based on an ?,? unsaturated ?-hydroxylactam structure, amongst others allowing a higher degree of functionalization compared to classical bioconjugation reactants such as maleimide. The present invention also provides methods of preparing the novel bioconjugation reactants, as well as uses thereof in human and/or veterinary medicine; and conjugation processes.
    Type: Application
    Filed: February 28, 2020
    Publication date: June 2, 2022
    Applicant: Universiteit Gent
    Inventors: Annemieke Madder, Ewout De Geyter, Eirini Antonatou, Sabina Smolen, Dimitris Kalaitzakis, Georgios Vassilikogiannakis
  • Methods for the site-selective coupling of a first agent to a second agent
    Patent number: 11053279
    Abstract: The present invention relates to a method for site-selective coupling of a first agent to a second agent, comprising the steps of: contacting a first agent comprising at least one furan moiety with an activation signal and with a second agent comprising at least one hydrazine moiety or at least one hydroxylamine moiety, thereby activating said furan moiety to an activated furan moiety; and reacting said activated furan moiety with the hydrazine moiety or the hydroxylamine moiety, thereby site-selectively coupling said first agent to said second agent.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: July 6, 2021
    Assignee: UNIVERSITEIT GENT
    Inventors: Annemieke Madder, Eirini Antonatou, Kurt Hoogewijs