Patents by Inventor Ekaterina Albert

Ekaterina Albert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cocrystals of progesterone
    Patent number: 9982007
    Abstract: The present invention relates to a cocrystal of progesterone and a coformer selected from the group consisting of vanillic acid, benzoic acid, salicylic acid, cinnamic acid, and vanillin. The present invention also relates to a pharmaceutical composition comprising a cocrystal of the present invention and at least one pharmaceutically acceptable carrier. The present invention further relates to a method of supplementing progesterone in women. This method involves administering to a female subject in need thereof a pharmaceutical composition of the present invention.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: May 29, 2018
    Assignee: AMRI SSCI, LLC
    Inventors: Ekaterina Albert, Patricia Andres, Melanie Janelle Bevill, Jared Smit, Jennifer Nelson
  • SOLID FORMS OF A BET INHIBITOR
    Publication number: 20180141939
    Abstract: Forms of (2-cyclopropyl-6-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-4-yl)di(pyridin-2-yl)methanol (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I.
    Type: Application
    Filed: November 10, 2017
    Publication date: May 24, 2018
    Inventors: Olga Viktorovna Lapina, Ekaterina Albert, Pavel R. Badalov, Jinyu Shen
  • Solid state forms of a PDE10 inhibitor
    Patent number: 9920045
    Abstract: The invention relates to a novel variable hydrate crystalline form of 1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-ethoxy-2-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)ethanone, methods for the preparation thereof, pharmaceutical compositions thereof and their use in the inhibition of PDE10.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: March 20, 2018
    Assignee: Omeros Corporation
    Inventors: Ekaterina Albert, Jennifer Leigh Nelson, Christopher Scott Seadeek, Karl Reineke, Marco Jonas, Suba Iyer, Xufeng Sun, Neil S. Cutshall, Jennifer Lynn Gage, Thomas L. Little, Wayne Douglas Luke, Elisabeth C. A. Brot, Michael James McDermott
  • SOLID STATE FORMS OF A PDE10 INHIBITOR
    Publication number: 20170166559
    Abstract: The invention relates to a novel variable hydrate crystalline form of 1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-ethoxy-2-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)ethanone, methods for the preparation thereof, pharmaceutical compositions thereof and their use in the inhibition of PDE10.
    Type: Application
    Filed: November 4, 2016
    Publication date: June 15, 2017
    Inventors: Ekaterina Albert, Jennifer Leigh Nelson, Christopher Scott Seadeek, Karl Reineke, Marco Jonas, Suba Iyer, Xufeng Sun, Neil S. Cutshall, Jennifer Lynn Gage, Thomas L. Little, Wayne Douglas Luke, Elisabeth C. A. Brot, Michael James McDermott
  • COCRYSTALS OF PROGESTERONE
    Publication number: 20170101433
    Abstract: The present invention relates to a cocrystal of progesterone and a coformer selected from the group consisting of vanillic acid, benzoic acid, salicylic acid, cinnamic acid, and vanillin. The present invention also relates to a pharmaceutical composition comprising a cocrystal of the present invention and at least one pharmaceutically acceptable carrier. The present invention further relates to a method of supplementing progesterone in women. This method involves administering to a female subject in need thereof a pharmaceutical composition of the present invention.
    Type: Application
    Filed: October 25, 2016
    Publication date: April 13, 2017
    Inventors: Ekaterina Albert, Patricia Andres, Melanie Janelle Bevill, Jared Smit, Jennifer Nelson
  • Cocrystals of progesterone
    Patent number: 9512166
    Abstract: Disclosed herein are cocrystals of progesterone and a coformer containing a six-membered aromatic ring having at least one substituent possessing a carbonyl functionality. Cocrystals of progesterone and a coformer selected from vanillic acid, benzoic acid, salicylic acid, cinnamic acid, or vanillin are also disclosed herein.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: December 6, 2016
    Assignee: AMRI SSCI, LLC
    Inventors: Ekaterina Albert, Patricia Andres, Melanie Janelle Bevill, Jared Smit, Jennifer Nelson
  • Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
    Patent number: 9150567
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: October 6, 2015
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Jiangao Song, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • SUBSTITUTED TETRAZOL-1-YL-PHENOXYMETHYL-THIAZOL-2-YL-PIPERIDINYL-PYRIMIDINE SALTS
    Publication number: 20150197518
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Application
    Filed: August 25, 2014
    Publication date: July 16, 2015
    Applicant: CYMABAY THERAPEUTICS, INC.
    Inventors: Jiangao Song, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • Crystalline forms and processes for their preparation
    Patent number: 8865913
    Abstract: The present invention relates to crystalline Form A of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione and crystalline Form B of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione, processes for preparing the forms and their uses in medicine. The present invention also relates to the amorphous form of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione processes for preparing it and its uses in medicine.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: October 21, 2014
    Assignee: Bial-Portela & CA, S.A.
    Inventors: Alexander Beliaev, David Alexander Learmonth, Brian Broadbelt, Ekaterina Albert, Patricia Andres
  • Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
    Patent number: 8815886
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: August 26, 2014
    Assignee: Cymabay Therapeutics, Inc.
    Inventors: Jiangao Song, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • COCRYSTALS OF PROGESTERONE
    Publication number: 20140235595
    Abstract: Disclosed herein are cocrystals of progesterone and a coformer containing a six-membered aromatic ring having at least one substituent possessing a carbonyl functionality. Cocrystals of progesterone and a coformer selected from vanillic acid, benzoic acid, salicylic acid, cinnamic acid, or vanillin are also disclosed herein.
    Type: Application
    Filed: September 4, 2013
    Publication date: August 21, 2014
    Applicant: Aptuit, Inc.
    Inventors: Ekaterina ALBERT, Patricia ANDRES, Melanie Janelle BEVILL, Jared SMIT, Jennifer NELSON
  • SUBSTITUTED TETRAZOL-1-YL-PHENOXYMETHYL-THIAZOL-2-YL-PIPERIDINYL-PYRIMIDINE SALTS
    Publication number: 20140038971
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Application
    Filed: March 28, 2013
    Publication date: February 6, 2014
    Applicant: Metabolex, Inc.
    Inventors: Jiangao SONG, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • Crystalline Forms and Processes for Their Preparation
    Publication number: 20140031561
    Abstract: The present invention relates to crystalline Form A of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione and crystalline Form B of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione, processes for preparing the forms and their uses in medicine. The present invention also relates to the amorphous form of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione processes for preparing it and its uses in medicine.
    Type: Application
    Filed: June 19, 2013
    Publication date: January 30, 2014
    Inventors: Alexander BELIAEV, David Alexander LEARMONTH, Brian BROADBELT, Ekaterina ALBERT, Patricia ANDRES
  • Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
    Patent number: 8410127
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: April 2, 2013
    Assignee: Metabolex, Inc.
    Inventors: Jiangao Song, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres
  • SUBSTITUTED TETRAZOL-1-YL-PHENOXYMETHYL-THIAZOL-2-YL-PIPERIDINYL-PYRIMIDINE SALTS
    Publication number: 20110152270
    Abstract: Crystalline salts of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Application
    Filed: September 20, 2010
    Publication date: June 23, 2011
    Inventors: Jiangao Song, Charles A. McWherter, Fang Ma, Mark Andres, Igor Ivanisevic, Ekaterina Albert, Patricia Andres