Patents by Inventor Ekaterina Feodorovna Kolesanova

Ekaterina Feodorovna Kolesanova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for poly signal activation of apoptosis of malignant solid tumour cells
    Patent number: 10603338
    Abstract: A method is provided for the poly signal activation of apoptosis of malignant solid tumour cells, carried out by means of the targeted delivery of thallium salts by surface-modified MS2 phage virions, which contain a cyclic iRGD ligand that has a high affinity for the integrins avb3 and avb5 and is covalently bound with the shell and with the core, which contains genomic RNA and thallium salts. Complex, efficient, prolonged cytotoxic action is provided on focal and metastatic clusters of malignant solid tumour cells, while minimizing undesirable side effects on the healthy cells of an organism.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: March 31, 2020
    Assignee: OBSHESTVO S ORGANICHENNOI OTVETSTVENNOST'YU “BIOTEHNOLOGIYA”
    Inventors: Tat'yana Nikolaevna Bol'shakova, Ekaterina Feodorovna Kolesanova, Ekaterina Ur'evna Rybalkina, Igor′ Gennad'evich Sivov
  • Method for Poly Signal Activation of Apoptosis of Malignant Solid Tumour Cells
    Publication number: 20180250331
    Abstract: The invention relates to medicine and concerns a method for the poly signal activation of apoptosis of malignant solid tumour cells, carried out by means of the targeted delivery of thallium salts by surface-modified MS2 phage virions which contain a cyclic iRGD ligand that has a high affinity for the integrins avb3 and avb5 and is covalently bound with the shell and with the core, which contains genomic RNA and thallium salts. The invention provides for complex, efficient, prolonged cytotoxic action on focal and metastatic clusters of malignant solid tumour cells, while minimizing undesirable side effects on the healthy cells of an organism.
    Type: Application
    Filed: October 21, 2016
    Publication date: September 6, 2018
    Inventors: Tat'yana Nikolaevna Bol'shakova, Ekaterina Feodorovna Kolesanova, Ekaterina Ur'evna Rybalkina, Igor' Gennad'evich Sivov