Patents by Inventor Ekaterina Vladimirovna SOFRONOVA

Ekaterina Vladimirovna SOFRONOVA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treatment of an IL-17A-mediated disease through antibody administration specific to human IL-17A
    Patent number: 11447574
    Abstract: The monoclonal IgG-type antibodies were suggested comprising variable domains represented by a combination of VHH-derivative with a variable domain of the light chain VL. Said antibodies can comprise amino acid substitutions at positions 44 and 45 (Kabat numbering) or combinations thereof. Antibodies of the invention possess increased affinity and improved aggregation stability.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: September 20, 2022
    Inventors: Andrey Borisovich Ulitin, Stanislav Rudolfovich Evdokimov, Valeriy Vladimirovich Soloviev, Yulia Sergeevna Chernykh, Olga Vladimirovna Goncharova, Dmitriy Valerievich Korzhavin, Tatyana Veniaminovna Chernovskaya, Timofey Aleksandrovich Nemankin, Roman Alexeevich Ivanov, Dmitriy Valentinovich Morozov, Victoria Mikhailovna Ekimova, Ekaterina Vladimirovna Sofronova, Yakov Yurevich Ustyugov
  • Monoclonal antibody to PD-L1
    Patent number: 11236167
    Abstract: The present invention relates to the field of biotechnology and provides antibodies that specifically binds to PD-L1. The invention also relates to DNA encoding said antibodies, to corresponding expression vectors and to methods of producing, and to methods of treatment using said antibodies.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: February 1, 2022
    Inventors: Andrei Borisovich Ulitin, Viktoriia Mikhailovna Ekimova, Ekaterina Vladimirovna Sofronova, Yulia Sergeevna Chernykh, Sergei Andreevich Ageev, Anna Konstantinovna Vladimirova, Aleksei Aleksandrovich Aleksandrov, Pavel Alekseevich Grebnev, Valery Vladimirovich Solovyev, Iakov Iurevich Ustiugov, Pavel Andreevich Iakovlev, Timofey Aleksandrovich Nemankin, Dmitry Valentinovich Morozov
  • MONOCLONAL ANTIBODY TO PD-L1
    Publication number: 20200369771
    Abstract: The present invention relates to the field of biotechnology and provides antibodies that specifically binds to PD-L1. The invention also relates to DNA encoding said antibodies, to corresponding expression vectors and to methods of producing, and to methods of treatment using said antibodies.
    Type: Application
    Filed: April 11, 2018
    Publication date: November 26, 2020
    Inventors: Andrey Borisovich ULITIN, Victoria Mikhailovna EKIMOVA, Ekaterina Vladimirovna SOFRONOVA,, Yulia Sergeevna CHERNYKH, Sergei Andreevich AGEEV, Anna Konstantinovna VLADIMIROVA, Aleksei Aleksandrovich ALEKSANDROV, Pavel Alekseevich GREBNEV, Valery Vladimirovich SOLOVYEV, Iakov Iurevich USTIUGOV, Pavel Andreevich IAKOVLEV, Timofey Aleksandrovich NEMANKIN, Dmitry Valentinovich MOROZOV
  • ANTI-IL-5RAlpha MONOCLONAL ANTIBODY
    Publication number: 20200291121
    Abstract: The present invention relates to biotechnology and provides antibodies that specifically bind to IL-5R?. The invention also relates to DNA encoding said antibodies, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibodies.
    Type: Application
    Filed: October 2, 2018
    Publication date: September 17, 2020
    Inventors: Ekaterina Vladimirovna SOFRONOVA, Aleksei Konstantinovich MISORIN, Aleksandr Nikolaevich DORONIN, Timofey Aleksandrovich NEMANKIN, Aleksandra Aleksandrovna SOZONOVA, Galina Stepanovna ZHIRIVSKAIA, Sergey Aleksandrovich LEGOTSKY, Anna Konstantinovna VLADIMIROVA, Alina Valerevna BELIASNIKOVA, Mariia Aleksandrovna SHCHEMELEVA, Pavel Andreevich IAKOVLEV, Valery Vladimirovich SOLOVYEV, Elena Andreevna KRENDELEVA, Natalia Evgenevna PESTOVA, Dmitry Valentinovich MOROZOV
  • HIGH AFFINITY AND AGGREGATIVELY STABLE ANTIBODIES ON THE BASIS OF VARIABLE DOMAINS VL AND A DERIVATIVE VHH
    Publication number: 20200031952
    Abstract: The monoclonal IgG-type antibodies were suggested comprising variable domains represented by a combination of VHH-derivative with a variable domain of the light chain VL. Said antibodies can comprise amino acid substitutions at positions 44 and 45 (Kabat numbering) or combinations thereof. Antibodies of the invention possess increased affinity and improved aggregation stability.
    Type: Application
    Filed: September 9, 2019
    Publication date: January 30, 2020
    Inventors: Andrey Borisovich ULITIN, Stanislav Rudolfovich EVDOKIMOV, Valeriy Vladimirovich SOLOVIEV, Yulia Sergeevna CHERNYKH, Olga Vladimirovna GONCHAROVA, Dmitriy Valerievich KORZHAVIN, Tatyana Veniaminovna CHERNOVSKAYA, Timofey Aleksandrovich NEMANKIN, Roman Alexeevich IVANOV, Dmitriy Valentinovich MOROZOV, Victoria Mikhailovna EKIMOVA, Ekaterina Vladimirovna SOFRONOVA, Yakov Yurevich USTYUGOV
  • Anti-IL-17A Antibodies
    Patent number: 10442869
    Abstract: The monoclonal IgG-type antibodies were suggested comprising variable domains represented by a combination of VHH-derivative with a variable domain of the light chain VL. Said antibodies can comprise amino acid substitutions at positions 44 and 45 (Kabat numbering) or combinations thereof. Antibodies of the invention possess increased affinity and improved aggregation stability.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: October 15, 2019
    Assignee: CLOSED JOINT STOCK COMPANY “BIOCAD”
    Inventors: Andrey Borisovich Ulitin, Stanislav Rudolfovich Evdokimov, Valeriy Vladimirovich Soloviev, Yulia Sergeevna Chernyh, Olga Vladimirovna Goncharova, Dmitriy Valerievich Korzhavin, Tatyana Veniaminovna Chernovskaya, Timofey Aleksandrovich Nemankin, Roman Alexeevich Ivanov, Dmitriy Valentinovich Morozov, Victoria Mikhailovna Ekimova, Ekaterina Vladimirovna Sofronova, Yakov Yurevich Ustyugov
  • HIGH AFFINITY AND AGGREGATIVELY STABLE ANTIBODIES ON THE BASIS OF VARIABLE DOMAINS VL AND A DERIVATIVE VHH
    Publication number: 20170066843
    Abstract: The monoclonal IgG-type antibodies were suggested comprising variable domains represented by a combination of VHH-derivative with a variable domain of the light chain VL. Said antibodies can comprise amino acid substitutions at positions 44 and 45 (Kabat numbering) or combinations thereof. Antibodies of the invention possess increased affinity and improved aggregation stability.
    Type: Application
    Filed: September 1, 2016
    Publication date: March 9, 2017
    Inventors: Andrey Borisovich ULITIN, Stanislav Rudolfovich EVDOKIMOV, Valeriy Vladimirovich SOLOVIEV, Yulia Sergeevna CHERNYH, Olga Vladimirovna GONCHAROVA, Dmitriy Valerievich KORZHAVIN, Tatyana Veniaminovna CHERNOVSKAYA, Timofey Aleksandrovich NEMANKIN, Roman Alexeevich IVANOV, Dmitriy Valentinovich MOROZOV, Victoria Mikhailovna EKIMOVA, Ekaterina Vladimirovna SOFRONOVA, Yakov Yurevich USTYUGOV