Patents by Inventor Ekihiro SEKI

Ekihiro SEKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for protecting liver and a liver protecting agent
    Patent number: 10780133
    Abstract: An object of the present invention is to provide a protective method for liver comprising the administration of an extract from inflamed tissues inoculated with vaccinia virus to a patient who needs the treatment and to provide a liver protective agent, etc. where such an extract is an active ingredient. In the present invention, it has been recognized that, in hepatocytes, activation of NF-B, expression of NF-B target genes, activation of JNK, apoptosis and fat accumulation can be inhibited or suppressed. The agent containing the extract as an active ingredient is a drug exhibiting less adverse action and high safety. Accordingly, the present invention provides very useful protective method for liver and liver protecting agent.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: September 22, 2020
    Assignees: NIPPON ZOKI PHARMACEUTICALS CO., LTD., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Ekihiro Seki, Koichi Masuda, Mitsuru Naiki
  • SYNTHETIC TLR4 AND TLR7 LIGANDS TO PREVENT, INHIBIT OR TREAT LIVER DISEASE
    Publication number: 20180110784
    Abstract: Methods of using TLR7 conjugates or TLR4 ligands, or a combination thereof, to treat fibrosis are provided.
    Type: Application
    Filed: April 7, 2016
    Publication date: April 26, 2018
    Inventors: Dennis A. Carson, Tomoko Hayashi, Ekihiro Seki
  • A METHOD FOR PROTECTING LIVER AND A LIVER PROTECTING AGENT
    Publication number: 20170224738
    Abstract: An object of the present invention is to provide a protective method for liver comprising the administration of an extract from inflamed tissues inoculated with vaccinia virus to a patient who needs the treatment and to provide a liver protective agent, etc. where such an extract is an active ingredient. In the present invention, it has been recognized that, in hepatocytes, activation of NF-B, expression of NF-B target genes, activation of JNK, apoptosis and fat accumulation can be inhibited or suppressed. The agent containing the extract as an active ingredient is a drug exhibiting less adverse action and high safety. Accordingly, the present invention provides very useful protective method for liver and liver protecting agent.
    Type: Application
    Filed: August 7, 2015
    Publication date: August 10, 2017
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NIPPON ZOKI PHARMACEUTICAL CO., LTD.
    Inventors: Ekihiro SEKI, Koichi MASUDA, Mitsuru NAIKI