Patents by Inventor Ekizabeth Jane Thomas

Ekizabeth Jane Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS
    Publication number: 20230116403
    Abstract: The present invention relates to compounds of formula (I) that function as inhibitors of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity: X—Y—Z??(I) wherein X, Y and Z are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, and autoimmune diseases, as well as other diseases or conditions in which METTL3 activity is implicated.
    Type: Application
    Filed: December 1, 2020
    Publication date: April 13, 2023
    Inventors: Wesley P. Blackaby, Ekizabeth Jane Thomas, David james Hardick, Jon Shepherd, Frederick Arthur Brookfield, Christian Bubert, Mark Peter Ridgill