Abstract: Methods for treating coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, are described. The methods can be used to reduce the severity of outcomes related to COVID-19, such as hospitalization and ventilation. For example, the methods can involve treatment of a subject with a therapeutic agent that degrades hyaluronan and/or an agent that neutralizes a hyaluronan receptor, e.g., CD44, such as an anti-CD44 antibody.

Abstract: A system and method for selectively configuring features and functions of a consolidated software application for particular end users.

Abstract: A method of producing a welded assembly from a first metal part and a second metal part includes bringing the first metal part and the second metal part into contact with one another at a joint region while providing a flash ring separator adjacent the joint region configured to intercept and separate flash. After heating the joint region, the first and second metal parts are forced together to join the first metal part to the second metal part, extruding metal flash from the joint region. The extruded flash impinges on the flash ring separator, forming a flash ring having at least one indentation. During subsequent machining of the welded assembly to remove the flash ring, the flash ring may fragment at the indentation, so that it does not cause damage by becoming hung around the assembly.

Abstract: A system and method for enhanced data transfer are disclosed, the method being applicable to a system comprising a computing device configured to transfer data from a portable device. In one embodiment, the computing device stores a fingerprint of the newest record downloaded from a portable device and stops downloading records from the device when a downloaded record matches the fingerprint. In another embodiment, the computing device stores a fingerprint of the newest record downloaded from a portable device and fully processes records that are downloaded from the device after a downloaded record matches the fingerprint. The system may include a portable device configured to adapt its operation responsive to a system fingerprint provided by the computing device. The portable device may be a medical device. The system may be a healthcare data management system.

Abstract: A system and method for enhanced data transfer are disclosed, the method being applicable to a system comprising a computing device configured to transfer data from a portable device. In one embodiment, the computing device stores a fingerprint of the newest record downloaded from a portable device and stops downloading records from the device when a downloaded record matches the fingerprint. In another embodiment, the computing device stores a fingerprint of the newest record downloaded from a portable device and fully processes records that are downloaded from the device after a downloaded record matches the fingerprint. The system may include a portable device configured to adapt its operation responsive to a system fingerprint provided by the computing device. The portable device may be a medical device. The system may be a healthcare data management system.

Abstract: A system and method for enhanced data transfer are disclosed, the method being applicable to a system comprising a computing device configured to transfer data from a portable device. In one embodiment, the computing device stores a fingerprint of the newest record downloaded from a portable device and stops downloading records from the device when a downloaded record matches the fingerprint. In another embodiment, the computing device stores a fingerprint of the newest record downloaded from a portable device and fully processes records that are downloaded from the device after a downloaded record matches the fingerprint. The system may include a portable device configured to adapt its operation responsive to a system fingerprint provided by the computing device. The portable device may be a medical device. The system may be a healthcare data management system.

Abstract: A system and method for enhanced data transfer are disclosed, the method being applicable to a system comprising a computing device configured to transfer data from a portable device. In one embodiment, the computing device stores a fingerprint of the newest record downloaded from a portable device and stops downloading records from the device when a downloaded record matches the fingerprint. In another embodiment, the computing device stores a fingerprint of the newest record downloaded from a portable device and fully processes records that are downloaded from the device after a downloaded record matches the fingerprint. The system may include a portable device configured to adapt its operation responsive to a system fingerprint provided by the computing device. The portable device may be a medical device. The system may be a healthcare data management system.

Abstract: A system and method for selectively configuring features and functions of a consolidated software application for particular end users.

Abstract: A system and method is provided for displaying a first selectable indicia that, when selected, produces a document of first help information relating to a first topic. The system and method also displaying a second selectable indicia that, when selected, produces a document of second help information relating to a chapter that includes the first topic.

Abstract: A system and method for activating selected features and functions of a software application during installation of software.

Abstract: An eye protective device for large animals such as horses wherein a flexible frame defining individual eye surrounding loops is secured on the animal's head and each loop mounts an outwardly bulging mesh panel that does not interfere with the animal's vision but bars passage of insects.