Patents by Inventor Elaine E. Hamm

Elaine E. Hamm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-C. difficile toxin antibodies and associated methods
    Patent number: 9957305
    Abstract: Embodiments of the invention are directed to a composition comprising a recombinant protein in soluble form wherein said recombinant protein comprises a portion of the Clostridium difficile toxin B sequence that comprises an epitope for anti-toxin B antibody. Other embodiments of the invention are directed to the generation of antibodies using peptide fragments of C. difficile toxin B.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: May 1, 2018
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Jimmy D. Ballard, Jordi M. Melton, Latisha Heinlen, Elaine E. Hamm
  • ANTI-C.DIFFICILE TOXIN ANTIBODIES AND ASSOCIATED METHODS
    Publication number: 20150104454
    Abstract: Embodiments of the invention are directed to a composition comprising a recombinant protein in soluble form wherein said recombinant protein comprises a portion of the Clostridium difficile toxin B sequence that comprises an epitope for anti-toxin B antibody. Other embodiments of the invention are directed to the generation of antibodies using peptide fragments of C. difficile toxin B.
    Type: Application
    Filed: September 13, 2012
    Publication date: April 16, 2015
    Applicant: Board of Regents of the University of Oklahoma
    Inventors: Jimmy D. Ballard, Jordi M. Melton, Latisha Heinlen, Elaine E. Hamm
  • Bacterial cells, optimized nucleotide sequences and methods for improved expression of recombinant toxin B
    Patent number: 8431361
    Abstract: In some embodiments, the present invention provides isolated nucleotide sequences that encode Clostridium difficile toxin B, wherein the isolated nucleotide sequences have been optimized for improved expression of the toxin B in a bacterial cell. Other embodiments of the present invention pertain to methods of expressing recombinant Clostridium difficile toxin B in a bacterial cell from the isolated nucleotide sequences of the present invention. In other embodiments, the present invention pertains to bacterial cells that comprise the isolated nucleotide sequences of the present invention. In further embodiments, the invention pertains to isolated peptides of recombinant Clostridium difficile toxin B that were derived from the isolated nucleotide sequences of the present invention.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: April 30, 2013
    Assignee: Board of Regents of The University of Oklahoma
    Inventors: Jimmy D. Ballard, Elaine E. Hamm, Jordi M. Melton
  • BACTERIAL CELLS, OPTIMIZED NUCLEOTIDE SEQUENCES AND METHODS FOR IMPROVED EXPRESSION OF RECOMBINANT CLOSTRIDIUM DIFFICILE TOXIN B
    Publication number: 20120070859
    Abstract: In some embodiments, the present invention provides isolated nucleotide sequences that encode Clostridium difficile toxin B, wherein the isolated nucleotide sequences have been optimized for improved expression of the toxin B in a bacterial cell. Other embodiments of the present invention pertain to methods of expressing recombinant Clostridium difficile toxin B in a bacterial cell from the isolated nucleotide sequences of the present invention. In other embodiments, the present invention pertains to bacterial cells that comprise the isolated nucleotide sequences of the present invention. In further embodiments, the invention pertains to isolated peptides of recombinant Clostridium difficile toxin B that were derived from the isolated nucleotide sequences of the present invention.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 22, 2012
    Inventors: Jimmy D. Ballard, Elaine E. Hamm, Jordi M. Melton