Abstract: The invention relates to a method of screening a patient to identify and quantify risk of colorectal cancer, and thereby identify patients suitable for further invasive investigation such as a colonoscopy. The method employs auto-antibodies that are shown to correlate with colorectal cancer risk method and involves of assaying a biological sample from the individual for a combination of a plurality of biomarkers selected from SEQUENCE ID NO's: 1 to 12, where the combination of biomarkers is chosen such that detection of all biomarkers in the patient correlates to at least a 50% risk of the patient being positive for colorectal cancer. Detection of all of the combination of biomarkers indicates that the patient should undergo a colonoscopy. Kits for performing the method of the invention are also provided.

Abstract: The invention relates to a method of screening a patient to identify and quantify risk of colorectal cancer, and thereby identify patients suitable for further invasive investigation such as a colonoscopy. The method employs auto-antibodies that are shown to correlate with colorectal cancer risk method and involves of assaying a biological sample from the individual for a combination of a plurality of biomarkers selected from SEQUENCE ID NO's: 1 to 12, where the combination of biomarkers is chosen such that detection of all biomarkers in the patient correlates to at least a 50% risk of the patient being positive for colorectal cancer. Detection of all of the combination of biomarkers indicates that the patient should undergo a colonoscopy. Kits for performing the method of the invention are also provided.

Abstract: A composite shipping container primarily for shipping bulk liquids consisting of an inner plastic tank held upright by an outer support structure of mesh wire side walls, a top wall and a bottom wall. This outer support structure forms a housing which is supported on a unitary tubular member pallet, which allows the composite shipping container to freely stand on a floor surface or stack upon a like composite shipping container. The unitary tubular member pallet is comprised of a single piece of metal tubing shaped into co-planar surfaces for the outer housing to rest on and shaped into feet to set the composite shipping container on a generally horizontal floor or other surface. The configuration of the unitary tubular member pallet reduces the amount of material required to complete the pallet and eases pallet construction.