Patents by Inventor Eldon Baird

Eldon Baird has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Publication number: 20070105135
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Application
    Filed: July 14, 2006
    Publication date: May 10, 2007
    Applicants: GeneSoft Pharmaceuticals, Inc., Genesoft, Inc.
    Inventors: Yigong Ge, Matthew Taylor, Eldon Baird, Heinz Moser, Roland Burli
  • Halogen-substituted thienyl compounds
    Publication number: 20060287247
    Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.
    Type: Application
    Filed: June 2, 2006
    Publication date: December 21, 2006
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Yigong Ge, Matthew Taylor, Eldon Baird, Roland Burli, Jacob Kaizerman, Amanda Martin, Brie Cadman
  • Biaryl compounds having anti-infective activity
    Publication number: 20060128747
    Abstract: Aromatic compounds exemplified by exhibit antimicrobial activity.
    Type: Application
    Filed: August 1, 2003
    Publication date: June 15, 2006
    Applicant: GENESOFT PHARMACEUTICALS,INC.
    Inventors: Roland Burli, Eldon Baird, Jacob Kaizerman, Dustin McMinn
  • Benzothiophene compounds having antiinfective activity
    Publication number: 20060116326
    Abstract: Benzothiophene compounds such as are DNA binding compounds exhibiting antibacterial activity.
    Type: Application
    Filed: November 30, 2004
    Publication date: June 1, 2006
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Roland Burli, Eldon Baird, Matthew Taylor, Jacob Kaizerman, Wenhao Hu
  • Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
    Patent number: 6683189
    Abstract: The present invention describes a novel method for the solid phase synthesis of polyamides containing imidazole and pyrrole carboxamides. The polyamides are prepared on a solid support from aromatic carboxylic acids and aromatic amines with high stepwise coupling yields (>99%), providing milligram quantities of highly pure polyamides. The present invention also describes the synthesis of analogs of the natural products Netropsin and Distamycin A, two antiviral antibiotics. The present invention also describes a novel method for the solid phase synthesis of imidazole and pyrrole carboxamide polyamide-oligonucleotide conjugates. This methodology will greatly increase both the complexity and quantity of minor-groove binding polyamides and minor-groove binding polyamide-oligonucleotide conjugates which can be synthesized and tested.
    Type: Grant
    Filed: July 22, 1999
    Date of Patent: January 27, 2004
    Assignee: California Institute of Technology
    Inventors: Peter B. Deryan, Eldon Baird
  • Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
    Patent number: 6090947
    Abstract: The present invention describes a novel method for the solid phase synthesis of polyamides containing imidazole and pyrrole carboxamides. The polyamides are prepared on a solid support from aromatic carboxylic acids and aromatic amines with high stepwise coupling yields (>99%), providing milligram quantities of highly pure polyamides. The present invention also describes the synthesis of analogs of the natural products Netropsin and Distamycin A, two antiviral antibiotics. The present invention also describes a novel method for the solid phase synthesis of imidazole and pyrrole carboxamide polyamide-oligonucleotide conjugates. This methodology will greatly increase both the complexity and quantity of minor-groove binding polyamides and minor-groove binding polyamide-oligonucleotide conjugates which can be synthesized and tested.
    Type: Grant
    Filed: February 26, 1996
    Date of Patent: July 18, 2000
    Assignee: California Institute of Technology
    Inventors: Peter B. Dervan, Eldon Baird