Patents by Inventor Elemer Fogassy

Elemer Fogassy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPTICALLY ACTIVE 3-[(PHENYLPIPERAZIN-1-YL)ALKYL]-3- ALKYL-OXINDOLE DERIVATIVES HAVING CNS ACTIVITY
    Publication number: 20120108607
    Abstract: The present invention relates to the enantiomers of 5,7-dichloro-3-{4-[4-(4-chlorophenyl)-piperazin-1-yl]butyl}-3-ethyl-1,3-dihydro-2H-indol-2-one of the Formula (II) pharmaceutically acceptable salts thereof, process for the preparation thereof, medicinal products containing said enantiomers and the use thereof and their pharmaceutically acceptable salts in the treatment of the disorders of the central nervous system.
    Type: Application
    Filed: February 5, 2010
    Publication date: May 3, 2012
    Inventors: Balázs Volk, József Barkóczy, István Gacsalyi, Elemér Fogassy, József Schindler, Gábor Gigler, Hajnalka Kompagne, Iidikó Nagyné Gyoenos, Katalin Pallagi, Márta Porcs-Makkay, Gábor Szénási, Tibor Mezel, Gyula Lukács, Gyoergy Lévay, András Egyed, László Gábor Hársing
  • Resolution process for (R)-(-)-2-hydroxy-2-(2-chlorophenyl) acetic acid
    Patent number: 7381835
    Abstract: The subject of the present invention is the preparation of the (R)-(?)-2-hydroxy-2-(2-chlorophenyl)acetic acid of the formula (I) by the resolution of the corresponding racemic compound by using the compounds of the general formula (II).
    Type: Grant
    Filed: June 14, 2002
    Date of Patent: June 3, 2008
    Assignee: Sanofi-Aventis
    Inventors: József Bálint, Marianna Csatáriné Nagy, Zsolt Dombrády, Elemér Fogassy, Antal Gajáry, Charles Suba
  • Resolution process for (r)-(-)-2-hydroxy-2-(2-chlorophenyl) acetic acid
    Publication number: 20040242921
    Abstract: The subject of the present invention is the preparation of the (R)-(−)-2-hydroxy-2-(2-chlorophenyl)acetic acid of the formula (I) by the resolution of the corresponding racernic compound by using the compounds of the general formula (II).
    Type: Application
    Filed: June 25, 2004
    Publication date: December 2, 2004
    Inventors: Jozsef Balint, Marianna Csatarine Nagy, Zsolt Dombrady, Elemer Fogassy, Antal Gajary, Charles Suba
  • Process for the resolution of threo-3-[(2-aminophenyl)-thio]-2-hydroxy-3-(4-methoxy-phenyl)propionic acid
    Patent number: 5292933
    Abstract: The invention relates to a novel process for the resolution of an acid mixture (hereinafter: threo acid mixture) containing (+)-threo-3-[(2-aminophenyl)thio]-2-hydroxy-3-(4-methoxyphenyl)-propionic acid [hereinafter: (+)-threo acid]and (-)-threo-3-[(2-aminophenyl)thio]-2-hydroxy-3-(4-methoxyphenyl)-propionic acid [hereinafter: (-)-threo acid].
    Type: Grant
    Filed: April 9, 1991
    Date of Patent: March 8, 1994
    Assignee: Richter Gedeon Vegyeszeti Gyar RT
    Inventors: Kalman Harsanyi, Elemer Fogassy, Maria cs, Tibor Gizur, Zsuzsanna Aracs nee Tischler, Katalin Berki, Laszlo Toke, Zsuzsanna Martonffy nee Jaszay
  • Diastereomer salts of phenylalanine and N-acyl derivatives thereof and process for the separation of optically active phenylalanine and N-acyl derivatives thereof
    Patent number: 4642205
    Abstract: The present invention relates to the separation of optically active phenylalanine and N-acyl derivatives thereof and novel diastereomer salts of the said compounds.According to the invention a racemic compound of the formula ##STR1## is reacted with an optically active resolving agent of the formula ##STR2## in a polar solvent and/or a mixture of solvents comprising at least one apolar solvent and optionally an achiral acid or base, thereafter(a) when using the D-isomer of the resolving agent of the formula II, the crystalline diastereomer salt formed with the L-isomer of the compound of the formula I is separated, or(b) when using the L-isomer of the resolving agent of the formula II, the crystalline diastereomer salt formed with the D-isomer of the compound of the formula I is separated, andthe enantiomers of the compound of the formula I from the diastereomer salt or the mother liquor are liberated by the aid of an achiral acid or base and the optically active product is separated in crystalline form.
    Type: Grant
    Filed: November 18, 1985
    Date of Patent: February 10, 1987
    Assignee: Alkaloida Vegyeszeti Gyar
    Inventors: Maria Acs, Ferenc Faigl, Elemer Fogassy
  • Process for the preparation of optically active cyclopropane carboxylic acids
    Patent number: 4508919
    Abstract: The invention relates to a process for the preparation of enantiomers of trans vinyl-cyclopropane carboxylic acids of the formula I, ##STR1## wherein R is a methyl group or chlorine atom, by resolution of racemic trans compound or mixture of racemic cis and trans compounds by using (+)- or (-)-N-(1-formamido-2,2,2-trichloroethyl)-piperazine as a resolving agent in a polar solvent then separating the crystallizing salt of (+)-trans carboxylic acid and (-)-resolving agent or (-)-trans carboxylic acid and (+)-resolving agent from the mother liquor by filtration and obtaining the enantiomers by acidifying the mother liquor or the salts suspended in water followed by extraction with a solvent and evaporation.The products so obtained may be used as starting materials for the preparation of insecticides.
    Type: Grant
    Filed: November 25, 1983
    Date of Patent: April 2, 1985
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Elemer Fogassy, Laszlo Toke, Ferenc Faigl, Rudolf Soos, Jozsef Bozzay, Rezso Kolta, Jozsef Nemes, Peter Bencsik