Patents by Inventor Elena Capito

Elena Capito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STERICALLY HINDERED AMINE STABILIZER MIXTURES
    Publication number: 20230159727
    Abstract: The present invention relates to mixtures of sterically hindered amines of the formulae (1) and (2) wherein at least one of the radicals Z1, Z2, Z3, Z4, Z5 and Z6 is C1-C18 alkyloxy or C5-C7 cycloalkyloxy and the remaining of the radicals Z1, Z2, Z3, Z4, Z5 and Z6 are hydrogen, hydroxy, C1-C18 alkyloxy or C5-C7 cycloalkyloxy, and at least one of the radicals Y1, Y2, Y3, Y4, Y5 and Y6 is a group of formula —CH2—CH?CH—R and the remaining of the radicals Y1, Y2, Y3, Y4, Y5 and Y6 are hydrogen or a group of formula —CH2—CH?CH—R, and the other substituents are as defined according to the present invention, methods for stabilization of an organic material, and a process for the preparation of compounds of formula (1?).
    Type: Application
    Filed: March 4, 2020
    Publication date: May 25, 2023
    Inventors: Manuele VITALI, Elisa MONTRONI, Matteo PORI, Elena CAPITO, Christian KRANEMANN
  • PROCESS FOR THE PREPARATION OF PIPERIDINE COMPOUNDS
    Publication number: 20230034961
    Abstract: The present invention relates to process for the preparation of a compound of formula (1), wherein R1 and R2 are independently from each other C1-C8alkyl, which comprises reacting a compound of formula (2), with a formaldehyde source in presence of a palladium or platinum catalyst at a hydrogen pressure of 5×108 mPa to 200×108 mPa.
    Type: Application
    Filed: December 14, 2020
    Publication date: February 2, 2023
    Inventors: Alexander Michael HAYDL, Michael SCHMITT, Klaus BECKER, Dirk BETHKE, Elena CAPITO', Johann-Peter MELDER
  • Oxyntomodulin analogs
    Patent number: 9593155
    Abstract: Peptide analogs of oxyntomodulin (OXM, glucagon-37), which have been modified to be resistant to cleavage and inactivation by dipeptidyl peptidase IV (DPP-IV) and to increase in vivo half-life of the peptide analog while enabling the peptide analog to act as a dual GLP-1/glucagon receptor (GCGR) agonist are described. The peptide analogs are useful for treatment of metabolic disorders such as diabetes and obesity.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: March 14, 2017
    Assignees: MERCK SHARP & DOHME CORP., MSD ITALIA S.R.L., INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
    Inventors: Paul E. Carrington, George J. Eiermann, Donald J. Marsh, Joseph M. Metzger, Alessandro Pocai, Ranabir Sinha Roy, Elisabetta Bianchi, Paolo Ingallinella, Antonello Pessi, Alessia Santoprete, Elena Capito, Richard Dimarchi, Brian Ward
  • OXYNTOMODULIN ANALOGS
    Publication number: 20150307580
    Abstract: Peptide analogs of oxyntomodulin (OXM, glucagon-37), which have been modified to be resistant to cleavage and inactivation by dipeptidyl peptidase IV (DPP-IV) and to increase in vivo half-life of the peptide analog while enabling the peptide analog to act as a dual GLP-1/glucagon receptor (GCGR) agonist are described. The peptide analogs are useful for treatment of metabolic disorders such as diabetes and obesity.
    Type: Application
    Filed: April 14, 2015
    Publication date: October 29, 2015
    Inventors: Paul E. CARRINGTON, George J. EIERMANN, Donald J. MARSH, Joseph M. METZGER, Alessandro POCAI, Ranabir SINHA ROY, Elisabetta BIANCHI, Paolo INGALLINELLA, Antonello PESSI, Alessia PRETE, Elena CAPITO, Richard DIMARCHI, Brian WARD
  • Pentacyclic indole derivatives as antiviral agents
    Patent number: 8232390
    Abstract: The present invention relates to pentacyclic indole derivatives of formula (I): wherein A, Ar, R1, R2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: July 31, 2012
    Assignee: Istituto di Richerche di Biologia Molecolare P. Angeletti SpA
    Inventors: Elena Capito, Joerg Habermann, Frank Narjes, Maria del Rosario Rico Ferreira, Ian Stansfield
  • OXYNTOMODULIN ANALOGS
    Publication number: 20120165503
    Abstract: Peptide analogs of oxyntomodulin (OXM, glucagon-37), which have been modified to be resistant to cleavage and inactivation by dipeptidyl peptidase IV (DPP-IV) and to increase in vivo half-life of the peptide analog while enabling the peptide analog to act as a dual GLP-1/glucagon receptor (GCGR) agonistm are described. The peptide analogs are useful for treatment of metabolic disorders such as diabetes and obesity.
    Type: Application
    Filed: December 18, 2009
    Publication date: June 28, 2012
    Inventors: Paul E. Carrington, George Eiermann, Donald Marsh, Joseph Metzger, Alessandro Pocai, Ranabir Sinha Roy, Bianchi Bianchi, Paolo Ingallinella, Antonello Pessi, Alessia Santoprete, Elena Capito, Richard Dimarchi, Brian Ward
  • Pentacyclic Indole Derivatives as Antiviral Agents
    Publication number: 20100009959
    Abstract: The present invention relates to pentacyclic indole derivatives of formula (I): wherein A, Ar, R1, R2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.
    Type: Application
    Filed: May 4, 2007
    Publication date: January 14, 2010
    Applicant: Instituto di Ricerche di Biologia Molecolare P. Angeletti SPA
    Inventors: Elena Capito, Joerg Habermann, Frank Narjes, Maria del Rosario Rico Ferreira, Ian Stansfield