Patents by Inventor Elena Cini

Elena Cini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleoside phosphoramidates useful for the treatment of viral infections and preparation thereof
    Patent number: 10407456
    Abstract: Two processes are described for preparing, in different diastereomeric purity degrees, the compound (S)-isopropyl-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)-phosphoryl)amino) propanoate, having the formula given below, known as Sofosbuvir and used for the treatment of hepatitis C.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: September 10, 2019
    Assignee: QUIMICA SINTETICA, S.A.
    Inventors: Giuseppe Barreca, Marcello Rasparini, Andrea Poggiali, Luca Carcone, Roberto Rocco Tufaro, Giovanni Marras, Maurizio Taddei, Elena Cini
  • NUCLEOSIDE PHOSPHORAMIDATES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS AND PREPARATION THEREOF
    Publication number: 20180118776
    Abstract: Two processes are described for preparing, in different diastereomeric purity degrees, the compound (S)-isopropyl-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)-phosphoryl)amino) propanoate, having the formula given below, known as Sofosbuvir and used for the treatment of hepatitis C.
    Type: Application
    Filed: March 25, 2016
    Publication date: May 3, 2018
    Inventors: Giuseppe BARRECA, Marcello RASPARINI, Andrea POGGIALI, Luca CARCONE, Roberto Rocco TUFARO, Giovanni MARRAS, Maurizio TADDEI, Elena CINI
  • 1,4-cyclohexylamine derivatives and processes for the preparation thereof
    Patent number: 9718795
    Abstract: The invention relates to a process for the synthesis of Cariprazine, an antipsychotic compound useful in the treatment of positive and negative symptoms associated to schizophrenia, with the following structural formula: (A) The invention further relates to the synthesis of intermediates useful in the preparation of Cariprazine.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: August 1, 2017
    Assignee: CHEMO RESEARCH, S.L.
    Inventors: Maurizio Taddei, Elena Cini, Marcello Rasparini
  • 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20160257661
    Abstract: The invention relates to a process for the synthesis of Cariprazine, an antipsychotic compound useful in the treatment of positive and negative symptoms associated to schizophrenia, with the following structural formula: (A) The invention further relates to the synthesis of intermediates useful in the preparation of Cariprazine.
    Type: Application
    Filed: October 14, 2014
    Publication date: September 8, 2016
    Inventors: Maurizio TADDEI, Elena CINI, Marcello RASPARINI
  • Process for producing Aliskiren
    Patent number: 9346745
    Abstract: A new route of synthesis of the compound Aliskiren of formula (I), used in the treatment of hypertension, is described.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: May 24, 2016
    Assignee: CHEMO IBERICA, S.A.
    Inventors: Maurizio Taddei, Adele Russo, Elena Cini, Renata Riva, Marcello Rasparini, Luca Carcone, Luca Banfi, Romina Vitale, Stephen Roseblade, Antonio Carlo Zanotti-Gerosa
  • Process for Producing Aliskiren
    Publication number: 20130071899
    Abstract: A new route of synthesis of the compound Aliskiren of formula (I), used in the treatment of hypertension, is described.
    Type: Application
    Filed: June 3, 2011
    Publication date: March 21, 2013
    Applicant: Chemo Iberica, S.A.
    Inventors: Maurizio Taddei, Adele Russo, Elena Cini, Renata Riva, Marcello Rasparini, Luca Carcone, Luca Banfi, Romina Vitale, Stephen Roseblade, Antonio Carlo Zanotti-Gerosa