Patents by Inventor Elena De Angelis

Elena De Angelis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIGAND THAT HAS BINDING SPECIFICITY FOR IL-4 AND/OR IL-13
    Publication number: 20110223168
    Abstract: The invention provides a dual-specific ligand comprising a first immunoglobulin variable domain having a first binding specificity and a complementary or non-complementary immunoglobulin variable domain having a second binding specificity.
    Type: Application
    Filed: May 19, 2011
    Publication date: September 15, 2011
    Inventors: Greg Winter, Ian Tomlinson, Olga Ignatovich, Lucy Holt, Elena De Angelis
  • Ligand
    Publication number: 20100081792
    Abstract: The invention provides a dual-specific ligand comprising a first and second single variable domain, each having binding specificity for a antigenic target. The invention also provides for a single variable domain monomer ligand that specifically binds to an antigenic target.
    Type: Application
    Filed: October 31, 2007
    Publication date: April 1, 2010
    Applicant: SmithKline Beecham Corporation
    Inventors: Steven Grant, Amrik Basran, Olga Ignatovich, Rudolph Maria T. De Wildt, Philip Jones, Neil Brewis, Ben Woolven, Elena De Angelis, Lucy J. Holt, Greg Winter, Ian Tomlinson, Kevin Moulder
  • Bispecific Ligands With Binding Specificity to Cell Surface Targets and Methods of Use Therefor
    Publication number: 20100021473
    Abstract: Disclosed are ligands comprising a first polypeptide domain having a binding site with binding specificity for a first cell surface target and a second polypeptide domain having a binding site for a second cell surface target, wherein each target are different and on the same cell. In some embodiments, the ligands described further comprise a toxin. In other embodiments, the ligands further comprise half-life extending moieties. Also disclosed are methods of using these ligands. In particular, the use of these ligands for cancer therapy is described.
    Type: Application
    Filed: December 5, 2006
    Publication date: January 28, 2010
    Applicant: DOMANTIS LIMITED
    Inventors: Elena De Angelis, Steve Holmes, Ian Tomlinson, Eric Yi-Chun Huang, Lucy J. Holt, Claire E. Everett
  • Ligand
    Publication number: 20060106203
    Abstract: The invention provides a dual-specific ligand comprising a first immunoglobulin variable domain having a first binding specificity and a complementary or non-complementary immunoglobulin variable domain having a second binding specificity.
    Type: Application
    Filed: December 28, 2004
    Publication date: May 18, 2006
    Inventors: Greg Winter, Ian Tomlinson, Olga Ignatovich, Lucy Holt, Elena De Angelis, Philip Jones