Patents by Inventor Elena GALFRE

Elena GALFRE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides
    Publication number: 20230346885
    Abstract: The present invention relates to novel peptides derived from various target proteins, complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: December 9, 2022
    Publication date: November 2, 2023
    Inventors: Alex Powlesland, Alfred Lim, Alina Popa, Andrew Brooks, Benjamin Oestringer, Chandramouli Reddy Chillakuri, Christopher Sayer, Dhaval Jaykant Sangani, Elena Galfre, Fiona Chester, Garret Keating, Graham Anthony Hood, Izabela Bombik, Johanne Pentier, Maurits Kleijnen, Meidai Sun, Nicole Mai, Philip Addis, Pietro Dellacristina, Sarah Gilgunn, Victoria Arena De Souza
  • PEPTIDES
    Publication number: 20210122794
    Abstract: The present invention relates to novel peptides derived from Calcium homeostasis modulator protein 3 (CALHM3), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 2, 2020
    Publication date: April 29, 2021
    Inventors: Alex POWLESLAND, Johanne PENTIER, Sarah GILGUNN, Elena GALFRE
  • PEPTIDES
    Publication number: 20210115099
    Abstract: The present invention provides a peptide comprising, consisting essentially of or consisting of (i) the amino acid sequence KMPEAGEEQPQV (SEQ ID NO: 1); (ii) the amino acid sequence ISQTPGINL (SEQ ID NO: 2); or (iii) the amino acid sequence of SEQ ID NO: 1 or 2 with the exception of 1, 2 or 3 amino acid substitutions and/or 1, 2 or 3 amino acid insertions, and/or 1, 2 or 3 amino acid deletions, wherein the peptide forms a complex with a Major Histocompatibility Complex (MHC) molecule. Also provided are a complex of the peptide a Major Histocompatibility Complex (MHC) molecule, a nucleic acid molecule comprising a nucleic acid sequence encoding the peptide, a vector comprising such a nucleic acid sequence, a cell comprising such a vector and a binding moiety that binds the peptide.
    Type: Application
    Filed: November 7, 2017
    Publication date: April 22, 2021
    Inventors: Alex POWLESLAND, Chandramouli CHILLAKURI, Dhaval SANGANI, Graham HOOD, Elena GALFRE
  • PEPTIDES
    Publication number: 20180327466
    Abstract: The present invention relates to novel peptides derived from Calcium homeostasis modulator protein 3 (CALHM3), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: November 15, 2018
    Inventors: Alex POWLESLAND, Johanne PENTIER, Sarach GILGUNN, Elena GALFRE