Patents by Inventor Elena Garcia-Fruitos

Elena Garcia-Fruitos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT ANTIMICROBIAL MULTIDOMAIN POLYPEPTIDE, METHODS OF PRODUCING AND USES THEREOF
    Publication number: 20220289867
    Abstract: A novel recombinant antimicrobial multidomain polypeptide in an aggregated and functional format is provided. The antimicrobial multidomain polypeptide comprises at least three peptidic domains: a) a non-enzymatic antimicrobial peptidic domain from mammal's immune system, b) a bacterial binding peptidic domain which interacts with the bacterial cell wall or membrane, and c) an enzymatic antimicrobial peptidic domain from mammal's immune system. The antimicrobial multidomain polypeptide exhibits a broad-spectrum antimicrobial effect and is produced in an efficient production system, i.e in form of inclusion bodies.
    Type: Application
    Filed: February 18, 2020
    Publication date: September 15, 2022
    Inventors: Elena GARCIA FRUITOS, Anna ARIS GIRALT, Ramon ROCA PINILLA, Adria LOPEZ CANO
  • Use of Inclusion Bodies as Therapeutic Agents
    Publication number: 20140308237
    Abstract: The present invention relates to the use of inclusion bodies as vehicles for therapeutic protein delivery. This method is applicable to the delivery of therapeutic proteins to intracellular locations. In addition, the invention also relates to the administration of a cell or a pharmaceutical composition comprising inclusion bodies formed by therapeutic proteins. These inclusion bodies formed by therapeutic proteins could be used for the treatment of different diseases.
    Type: Application
    Filed: November 15, 2013
    Publication date: October 16, 2014
    Applicants: Centro de Investigacion Biomedica en Red en Bioin- genieria, Biomateriales, y Nanomedicina (Ciber BB, Universitat Autonoma de Barcelona et al.
    Inventors: Elena GARCIA-FRUITOS, Esther VAZQUEZ GOMEZ, Jose Luis CORCHERO NIETO, Antonio Pedro VILLAVERDE CORRALES
  • Use of Inclusion Bodies as Therapeutic Agents
    Publication number: 20120148529
    Abstract: The present invention relates to the use of inclusion bodies as vehicles for therapeutic protein delivery. This method is applicable to the delivery of therapeutic proteins to intracellular locations. In addition, the invention also relates to the administration of a cell or a pharmaceutical composition comprising inclusion bodies formed by therapeutic proteins. These inclusion bodies formed by therapeutic proteins could be used for the treatment of different diseases.
    Type: Application
    Filed: May 12, 2010
    Publication date: June 14, 2012
    Applicants: Centro de Invesigacion Biomedica en Red en Bioiagenieria, Biomateriales, y Nanomedicina (Cibe, Universitat Autonoma de Barcelona et al.
    Inventors: Elena Garcia-Fruitos, Esther Vazquez Gomez, Jose Luis Corchero, Antonio Pedro Villa Verde Corrales
  • INCLUSION BODIES, BACTERIAL CELLS AND COMPOSITIONS CONTAINING THEM AND USES THEREOF
    Publication number: 20110268773
    Abstract: The present invention relates to an isolated inclusion body comprising a polypeptide, characterised in that such inclusion body is in particulate form. The present invention also refers to a bacterial cell comprising said inclusion body. The present invention additionally refers to a composition comprising said inclusion body and a eukaryotic cell. The present invention moreover refers to a composition comprising said inclusion body and animal or plant tissue. The present invention furthermore refers to the uses of said inclusion body as medicaments and cell-proliferation stimulators and tissue regenerators.
    Type: Application
    Filed: December 22, 2009
    Publication date: November 3, 2011
    Applicants: UNIVERSITAT AUTÒNOMA DE BARCELONA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS
    Inventors: Jaume Veciana Miro, Inmaculada Ratera Bastardas, César Díez Gil, Antonio Pedro Villaverde Corrales, Esther Vázquez Gómez, Elena García Fruitós