Patents by Inventor Elena Klyachko

Elena Klyachko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Producing L-Histidine Using Bacteria of Enterobacteriaceae Family
    Publication number: 20070184532
    Abstract: A method is provided for producing L-histidine using bacterium of the Enterobacteriaceae family, wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of the transaldolase encoded by the talB gene.
    Type: Application
    Filed: April 4, 2007
    Publication date: August 9, 2007
    Inventors: Elena Klyachko, Rustam Shakulov, Yuri Kozlov
  • Method for producing L-amino acids using bacteria of the Enterobacteriaceae family
    Publication number: 20060088919
    Abstract: There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease.
    Type: Application
    Filed: October 12, 2005
    Publication date: April 27, 2006
    Inventors: Konstantin Rybak, Ekaterina Slivinskaya, Ekaterina Savrasova, Valeriy Akhverdian, Elena Klyachko, Sergei Mashko, Vera Doroshenko, Larisa Airikh, Tatyana Leonova, Mikhail Gusyatiner, Elvira Voroshilova, Yury Kozlov, Yoshihiko Hara, Takuji Ueda
  • Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
    Publication number: 20050214911
    Abstract: A method for producing an L-amino acid, such as L-histidine, L-threonine, L-lysine, L-glutamic acid, and L-tryptophan, using bacterium belonging to the genus Escherichia which has increased expression of genes, such as those of the xylABFGHR locus, which encode the xylose utilization enzymes, is disclosed. The method includes cultivating the L-amino acid producing bacterium in a culture medium containing xylose, and collecting the L-amino acid from the culture medium.
    Type: Application
    Filed: March 15, 2005
    Publication date: September 29, 2005
    Inventors: Aleksey Marchenko, Sergey Benevolensky, Elena Klyachko, Yuri Kozlov, Elvira Voroshilova, Mikhail Gusyatiner
  • Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
    Publication number: 20050214913
    Abstract: A method for producing an L-amino acid, such as L-histidine, using bacterium belonging to the genus Escherichia having increased expression amount of genes, such as xylABFGHR locus, coding for xylose utilization enzymes, is disclosed. The method comprises cultivating the L-amino acid producing bacterium in a culture medium containing xylose, and collecting the L-amino acid from the culture medium.
    Type: Application
    Filed: February 17, 2005
    Publication date: September 29, 2005
    Inventors: Aleksey Marchenko, Sergey Benevolensky, Elena Klyachko, Yuri Kozlov
  • Mutant phosphoribosylpyrophosphate synthetase and method for producing L-histidine
    Publication number: 20050176033
    Abstract: The present invention relates to a mutant bacterial PRPP synthetase which is resistant to feedback by purine nucleotides, and a method for producing L-histidine using the bacterium of the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by use of the PRPP synthetase which is resistant to feedback by purine nucleotides, coded by the mutant prsA gene.
    Type: Application
    Filed: November 10, 2004
    Publication date: August 11, 2005
    Inventors: Elena Klyachko, Rustem Shakulov, Yuri Kozlov
  • Method for producing L-histidine using bacteria of Enterobacteriaceae family
    Publication number: 20050054061
    Abstract: A method is provided for producing L-histidine using bacterium of the Enterobacteriaceae family, wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of the transaldolase encoded by the talb gene.
    Type: Application
    Filed: July 16, 2004
    Publication date: March 10, 2005
    Inventors: Elena Klyachko, Rustam Shakulov, Yuri Kozlov
  • Method for producing L-histidine using bacteria of Enterobacteriaceae family
    Publication number: 20050048631
    Abstract: A method is provided for producing L-histidine using bacterium of the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of the AICAR transformylase-IMP cyclohydrolase encoded by the purH gene.
    Type: Application
    Filed: August 27, 2004
    Publication date: March 3, 2005
    Inventors: Elena Klyachko, Rustem Shakulov, Yuri Kozlov