Patents by Inventor Elena Klyushnenkova

Elena Klyushnenkova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT T CELL RECEPTOR LIGAND COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CANCER
    Publication number: 20170196957
    Abstract: Disclosed herein are compositions and methods for treating or inhibiting prostate cancer. The compositions include a MHC molecule including covalently linked first and second domains, wherein the first domain is an MHC class II ?1 domain and the second domain is an MHC class II ?1 domain, wherein the amino terminus of the ?1 domain is covalently linked to the carboxy terminus of the ?1 domain, and a prostate specific antigen peptide covalently linked to the first domain. The methods include administering a disclosed MHC molecule to a subject with prostate cancer.
    Type: Application
    Filed: January 6, 2017
    Publication date: July 13, 2017
    Applicants: Oregon Health & Science University, The United States Government as Represented by the Department of Veterans Affairs, University of Maryland, Baltimore
    Inventors: Arthur A. Vandenbark, Roberto Meza-Romero, Richard Alexander, Elena Klyushnenkova
  • Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
    Patent number: 6875430
    Abstract: A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of mesenchymal stem cells effective to reduce or inhibit host rejection of the transplant. The mesenchymal stem cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with mesenchymal stem cells.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: April 5, 2005
    Assignee: Osiris Therapeutics, Inc.
    Inventors: Kevin R. McIntosh, Joseph D. Mosca, Elena Klyushnenkova
  • Suppressor cells induced by culture with mesenchymal stem cells for treatment of immune responses in transplantation
    Patent number: 6685936
    Abstract: A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of suppressor T cells effective to reduce or inhibit host rejection of the transplant. The suppressor T cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with suppressor T cells.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: February 3, 2004
    Assignee: Osiris Therapeutics, Inc.
    Inventors: Kevin McIntosh, Elena Klyushnenkova
  • Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
    Publication number: 20020085996
    Abstract: A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of mesenchymal stem cells effective to reduce or inhibit host rejection of the transplant. The mesenchymal stem cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with mesenchymal stem cells.
    Type: Application
    Filed: November 13, 2001
    Publication date: July 4, 2002
    Inventors: Kevin R. McIntosh, Joseph D. Mosca, Elena Klyushnenkova
  • SUPPRESSOR CELLS FOR PREVENTION AND TREATMENT OF IMMUNE RESPONSES IN TRANSPLANTATION
    Publication number: 20020034504
    Abstract: A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of suppressor T cells effective to reduce or inhibit host rejection of the transplant. The suppressor T cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with suppressor T cells.
    Type: Application
    Filed: October 12, 1999
    Publication date: March 21, 2002
    Inventors: KEVIN MCINTOSH, ELENA KLYUSHNENKOVA
  • Method of preparing suppressor T cells with allogeneic mesenchymal stem cells
    Patent number: 6281012
    Abstract: A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of suppressor T cells effective to reduce or inhibit host rejection of the transplant. The suppressor T cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with suppressor T cells.
    Type: Grant
    Filed: May 1, 2000
    Date of Patent: August 28, 2001
    Assignee: Osiris Therapeutics, Inc.
    Inventors: Kevin McIntosh, Elena Klyushnenkova