Publication number: 20190365784
Abstract: Brassinosteroid analogs used for the treatment of dermal disorders or conditions. One embodiment is the topical application of at least one brassinosteroid analog for the treatment of psoriasis in a mammal, the brassinosteroid analogs being of general formula (a). (a) (I) where, R1, R2, and R3 are selected from H, HO—, linear or branched C1-C4 alkyl, R5—O—, HCOO—, R5—COO—, —OOC—R6—COO—, p-toluene sulphonate, phosphate, tartrate, maleate, sulphate, fluorine, chlorine, bromine, iodine and methanesulphonate, R4 and R5 are selected from H and linear or branched C1-C4 alkyl, R6 is —(CH2)n- wherein n equals to 1, 2 or 3, and can be a single or double bond. A method of therapeutic treatment for psoriasis, skin aging, rosacea, dermatitis, burns, skin cancer and malignancies, and pigmentary derangements, by element of administration of brassinosteroid analogs of general formula (a).
Type:
Application
Filed:
December 29, 2016
Publication date:
December 5, 2019
Inventors:
José GROISMAN, Felipe INSERRA, Elena MARTINEZ VIVOT, Emilio SOJO