Patents by Inventor Elena N. Padeiskaya

Elena N. Padeiskaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole derivative having antiviral, interferon-inducing and immunomodulatory effects
    Patent number: 5198552
    Abstract: A novel compound--ethyl 6-bromo-5-hydroxy-4-dimethylaminomethyl-1-methyl-2-phenylthiomethylindole- 3- carboxylate hydrochloride monohydrate having the following formula: ##STR1## A process for preparing the compound according to the invention, characterized in that it comprises treating ethyl 5-acetoxy-1,2-dimethylindole-3-carboxylate with a brominating agent in an inert organic solvent under reflux, reacting the resultant ethyl 5-acetoxy-6-bromo-2-bromomethyl-1-methylindole-3-carboxylate with thiophenol in the presence of an alkali metal hydroxide or its alcoholate in an organic solvent, reacting the resultant ethyl 6-bromo-5-hydroxy-1-methyl-2-phenylthiomethylindole-3-carboxylate with an aminomethylating agent in an organic solvent at a temperature of from 65.degree. C. to a temperature of refluxing the reaction mixture. The end product is then isolated from the resultant base--ethyl 6-bromo-5-hydroxy-4-dimethylaminomethyl-1-methyl-2-phenylthiomethylindole- 3- carboxylate.
    Type: Grant
    Filed: November 12, 1991
    Date of Patent: March 30, 1993
    Inventors: Fedor A. Trofimov, Nina G. Tsyshkova, Nadezhda S. Bogdanova, Irina S. Nikolaeva, Svetlana A. Zotova, Zinaida M. Sakhaschik, Elena N. Padeiskaya, Alla N. Fomina, Evgenia A. Svirina, Dmitry M. Zlydnikov, Olga I. Kubar, Evgenia G. Shvetsova, Svetlana N. Kutchak, Valentina V. Peters, Elena A. Bryantseva, Anatoly G. Konoplyannikov, Boris P. Surinov, Vera A. Yadrovskaya, Ljudmila S. Safonova, Nina A. Karpova, Elena P. Savina, Ljudmila A. Savinova, Alexei N. Grinev, deceased, Grigory N. Pershin, deceased, Galina V. Grineva, Ellina G. Pershina
  • Joining element for fixation of bone tissues
    Patent number: 4550723
    Abstract: According to the present invention there is provided a joining element for fixation of bone tissues, which is made essentially as an oblong solid provided with recesses, wherein are made fast inserts of a biologically compatible polymer, containing a physiologically active medical preparations.
    Type: Grant
    Filed: February 17, 1984
    Date of Patent: November 5, 1985
    Inventors: Sergei I. Belykh, Anatoly B. Davydov, Igor L. Kovalenko, Lidia Y. Loktionova, Anatoly D. Moschensky, Gely G. Pershin, Grigory N. Pershin, Elena N. Padeiskaya, Lidia M. Polukhina, Nikolai I. Ochirov, Jury I. Filippov
  • Joining element for fixation of bone tissues
    Patent number: 4375810
    Abstract: According to the present invention there is provided a joining element for fixing bone tissues, which is made essentially as an oblong solid provided with recesses, wherein are made fast inserts of a biologically compatible polymer, containing a physiologically active medical preparations.
    Type: Grant
    Filed: January 4, 1980
    Date of Patent: March 8, 1983
    Inventors: Sergei I. Belykh, Anatoly B. Davydov, Igor L. Kovalenko, Lidia Y. Loktionova, Anatoly D. Moschensky, Gely G. Pershin, Grigory N. Pershin, Elena N. Padeiskaya, Lidia M. Polukhina, Nikolai I. Ochirov, Jury I. Filippov