Patents by Inventor Elena Terentieva

Elena Terentieva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fermentative production of mannitol
    Patent number: 7358072
    Abstract: The invention provides processes for continuous fed-batch fermentative production and continuous recycle fermentative production of mannitol.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: April 15, 2008
    Assignees: ZuChem, Inc, The United States of America as represented by the Secretary of Agriculture
    Inventors: Badal Saha, Francis Michael Racine, Elena Terentieva
  • Fermentative production of mannitol
    Publication number: 20060134765
    Abstract: The invention provides processes for continuous fed-batch fermentative production and continuous recycle fermentative production of mannitol.
    Type: Application
    Filed: October 14, 2005
    Publication date: June 22, 2006
    Applicant: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Badal Saha, Francis Racine, Elena Terentieva
  • Optically active fluorinated vasoconstrictors, methods for making them, and anesthetic formulations comprising them
    Patent number: 6900203
    Abstract: (R)-6F-phenylephrine, essentially free of (S)-6F-phenylephrine, and an anesthetic formulation comprising (R)-6F-epinephrin or (R)-6F-phenylephrine and having improved stability compared to formulations containing their non-fluorinated analog, are disclosed. Further disclosed is a method of providing vasoconstriction in a mammal by administering the anesthetic formulation. The anesthetic composition can include an anesthetic, an (R)-chiral compound having the structure: wherein R1, R2, and R4 are independently selected from —H or —F, at least one of R1, R2, and R4 is —F, and R3 is selected from —OH, —H or —F, or a pharmaceutically acceptable salt or ester thereof, said vasoconstrictor being essentially free of the (S)-chiral form. Also, a method of chiral addition of cyanide to a ring-fluorinated phenaldehyde, employing an almond hydroxynitrile lyase enzyme, provided in the form of a reversibly soluble polymer conjugate ((R)-Finezyme™-H series biocatalysts) is disclosed.
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: May 31, 2005
    Assignee: Polium Technologies, Inc.
    Inventors: Hamilton J. Lenox, Elena Terentieva, Mikhail Y. Gololobov
  • Optically active fluorinated vasoconstrictors, methods for making them, and anesthetic formulations comprising them
    Publication number: 20040002549
    Abstract: (R)-6F-phenylephrine, essentially free of (S)-6F-phenylephrine, and an anesthetic formulation comprising (R)-6F-epinephrin or (R)-6F-phenylephrine and having improved stability compared to formulations containing their non-fluorinated analog, are disclosed. Further disclosed is a method of providing vasoconstriction in a mammal by administering the anesthetic formulation.
    Type: Application
    Filed: July 8, 2002
    Publication date: January 1, 2004
    Inventors: Hamilton J. Lenox, Elena Terentieva, Mikhail Y. Gololobov