Patents by Inventor Elena Tomasello

Elena Tomasello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides associated with activatory receptors and their biological applications
    Patent number: 7569666
    Abstract: The invention concerns novel means for diagnosing, preventing, compensating, treating an abnormal or unwanted functioning of KAR receptors (Killer cell Activatory Receptor), counterparts of non-inhibiting KIR receptors (Keller cell Inhibitory Receptors) of the immunoglobulin or lectin type. The invention concerns in particular, novel KARAP (KAR-Associated Proteins) polypeptides and their biological applications. A KARAP polypeptide is naturally associated with a KAR receptor, and in the absence of such a KARAP, said KAR receptor is naturally incapable of transducing an activating signal that can be detected. The application also concerns methods for obtaining or identifying such KARAP polypeptides.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: August 4, 2009
    Assignee: Institut National de la Sante et de la Recherche Medicale
    Inventors: Eric Vivier, Alessandro Moretta, Lucia Olcese, Frédéric Vely, Elena Tomasello
  • Polypeptides associated with activatory receptors and their biological applications
    Publication number: 20050130130
    Abstract: The invention concerns novel means for diagnosing, preventing, compensating, treating an abnormal or unwanted functioning of KAR receptors (Killer cell Activatory Receptor, counterparts of non-inhibiting KIR receptors (Keller cell Inhibitory Receptors) of the immunoglobulin or lectin type. The invention concerns in particular, novel KARAP (KAR-Associated Proteins) polypeptides and their biological applications. A KARAP polypeptide is naturally associated with a KAR receptor, and in the absence of such a KARAP, said KAR receptor is naturally incapable of transducing an activating signal that can be detected. The application also concerns methods for obtaining or identifying such KARAP polypeptides.
    Type: Application
    Filed: August 2, 2004
    Publication date: June 16, 2005
    Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Eric Vivier, Alessandro Moretta, Lucia Olcese, Frederic Vely, Elena Tomasello
  • Means for the identification compounds capable of inhibiting karap-transduced signals
    Publication number: 20040045041
    Abstract: The present application relates to transgenic animals over-expressing KARAP, knock-in animals bearing non functional KARAP, and to method and kits for the identification of compounds capable of inhibiting a KARAP-transduced immune signal.
    Type: Application
    Filed: August 18, 2003
    Publication date: March 4, 2004
    Inventors: Eric Vivier, Frederic Vely, Elena Tomasello