Patents by Inventor Elena V. Kurenova

Elena V. Kurenova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kinase protein binding inhibitors
    Patent number: 9394253
    Abstract: The invention relates to protein binding inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating cell proliferative disorders, especially cancer.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: July 19, 2016
    Assignee: Health Research, Inc.
    Inventors: William G. Cance, Ravindra K. Pandey, Elena V. Kurenova, Manivannan Ethirajan
  • KINASE PROTEIN BINDING INHIBITORS
    Publication number: 20150051245
    Abstract: The invention relates to protein binding inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating cell proliferative disorders, especially cancer.
    Type: Application
    Filed: November 13, 2012
    Publication date: February 19, 2015
    Inventors: William G. Cance, Ravindra K. Pandey, Elena V. Kurenova, Manivannan Ethirajan
  • KINASE PROTEIN BINDING INHIBITORS
    Publication number: 20140194477
    Abstract: The invention relates to phosphorylation inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating cell proliferative disorders, especially cancer.
    Type: Application
    Filed: October 8, 2013
    Publication date: July 10, 2014
    Applicant: Roswell Park Cancer Institute
    Inventors: William G. Cance, Vita Golubovskaya, Elena V. Kurenova
  • METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS
    Publication number: 20120164141
    Abstract: The C-terminal domain of focal adhesion kinase (FAK-CD) was isolated using a Baculoviral system. Using phage display techniques, a phage encoding a 12 amino-acid peptide (peptide 35) and AV3 that binds to FAK-CD were identified. The peptides were also conjugated to TAT-FITC to produce a fluorescently labeled chimeric molecule capable of penetrating cell membranes. Contacting various breast cancer cell lines with these molecule caused detachment, rounding, apoptosis and cell death. These effects were not observed in normal (non-cancerous) breast cells.
    Type: Application
    Filed: August 22, 2011
    Publication date: June 28, 2012
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: William G. Cance, Vita Golubovskaya, Elena V. Kurenova
  • Methods and compositions for inducing apoptosis
    Patent number: 8003613
    Abstract: The C-terminal domain of focal adhesion kinase (FAK-CD) was isolated using a Baculoviral system. Using phage display techniques, a phage encoding a 12 amino-acid peptide (peptide 35) and AV3 that binds to FAK-CD were identified. The peptides were also conjugated to TAT-FITC to produce a fluorescently labeled chimeric molecule capable of penetrating cell membranes. Contacting various breast cancer cell lines with these molecule caused detachment, rounding, apoptosis and cell death. These effects were not observed in normal (non-cancerous) breast cells.
    Type: Grant
    Filed: November 17, 2004
    Date of Patent: August 23, 2011
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: William G. Cance, Vita Golubovskaya, Elena V. Kurenova