Patents by Inventor Eleni Maria VARYPATAKI

Eleni Maria VARYPATAKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOCONJUGATES
    Publication number: 20230192795
    Abstract: The present invention generally relates to mutant interleukin-7 polypeptides, immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-7 polypeptide and an antibody that binds to PD-1. In addition, the invention relates to polynucleotide molecules encoding the mutant interleukin-7 polypeptides or the immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. The invention further relates to methods for producing the mutant interleukin-7 polypeptides, immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.
    Type: Application
    Filed: April 13, 2021
    Publication date: June 22, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Laura Codarri Deak, Anne Freimoser-Grundschober, Christian Klein, Laura Lauener, Ekkehard Moessner, Cindy Schulenburg, Pablo Umaña, Eleni Maria Varypataki
  • METHOD FOR DIAGNOSING CUTANEOUS T-CELL LYMPHOMA DISEASES
    Publication number: 20230028910
    Abstract: The present invention relates to a method for diagnosing Sézary syndrome or mycosis fungoides in a subject. The present invention further relates to a method for determining the frequency of Sézary signature cells and/or mycosis fungoides cells in a sample. Further, the present invention relates to a computer-implemented method comprising a classifier algorithm to determine the frequency of Sézary signature cells and/or mycosis fungoides cells. In addition the present invention relates to a panel of biomarkers that can be used for the diagnosis of Sézary syndrome or mycosis fungoides.
    Type: Application
    Filed: November 13, 2020
    Publication date: January 26, 2023
    Inventors: Peter NESTOROV, Vijay Kumar TIWARI, Manfred CLAASSEN, Philip KNUCKLES, Sarah HAMILTON CARL, Emmanuella GUENOVA, Christina FASSNACHT, Eleni Maria VARYPATAKI