Patents by Inventor Eleni Markousta

Eleni Markousta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF DELIVERING GENES AND DRUGS TO A POSTERIOR SEGMENT OF AN EYE
    Publication number: 20210369863
    Abstract: A multifunctional dendrimer nanoparticle and method of treating diseases of the posterior segment of the eye is presented. The functionalized polyamidoamine (PAMAM) dendrimer effectively delivers drugs and/or genes to the posterior eye, thereby providing for the effective, non-invasive, and topical treatment of diseased in the posterior eye. The multifunctional dendrimer nanoparticle has shRNA-encoding DNA and small molecule drug encapsulated cyclodextrin complexed to the outer surface of the dendrimer for delivery to the posterior segment of the eye.
    Type: Application
    Filed: August 6, 2021
    Publication date: December 2, 2021
    Applicant: The United States Government as Represented by the Department of Veterans Affair
    Inventors: Shyam S. Mohapatra, Subhra Mohapatra, Eleni Markousta
  • Method of delivering genes and drugs to a posterior segment of an eye
    Patent number: 11110183
    Abstract: A multifunctional dendrimer nanoparticle and method of treating diseases of the posterior segment of the eye is presented. The functionalized polyamidoamine (PAMAM) dendrimer effectively delivers drugs and/or genes to the posterior eye, thereby providing for the effective, non-invasive, and topical treatment of diseased in the posterior eye. The multifunctional dendrimer nanoparticle has shRNA-encoding DNA and small molecule drug encapsulated cyclodextrin complexed to the outer surface of the dendrimer for delivery to the posterior segment of the eye.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: September 7, 2021
    Assignees: University of South Florida, The United States Government as Represented by the Department of Veterans Affairs
    Inventors: Shyam S. Mohapatra, Subhra Mohapatra, Eleni Markousta
  • METHOD OF DELIVERING GENES AND DRUGS TO A POSTERIOR SEGMENT OF AN EYE
    Publication number: 20200061207
    Abstract: A multifunctional dendrimer nanoparticle and method of treating diseases of the posterior segment of the eye is presented. The functionalized polyamidoamine (PAMAM) dendrimer effectively delivers drugs and/or genes to the posterior eye, thereby providing for the effective, non-invasive, and topical treatment of diseased in the posterior eye. The multifunctional dendrimer nanoparticle has shRNA-encoding DNA and small molecule drug encapsulated cyclodextrin complexed to the outer surface of the dendrimer for delivery to the posterior segment of the eye.
    Type: Application
    Filed: August 5, 2019
    Publication date: February 27, 2020
    Applicants: University of South Florida, The United Government as Represented by the Department of Veterans Affair
    Inventors: Shyam S. Mohapatra, Subhra Mohapatra, Eleni Markousta