Patents by Inventor Eleonora Alterman

Eleonora Alterman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High purity peptides
    Publication number: 20080287650
    Abstract: The invention relates to methods for the preparation of highly purified peptides. The peptides are prepared in high optical purity of at least about 98.5%, and preferably at least about 99%. Specifically, Nesiritide (SEQ. ID NO. 1) having a purity of at least 99% as measured by HPLC and containing about 0.05% to about 0.5% [D-His]-Nesiritide (SEQ. ID NO. 1) as measured by chiral GC/MS.
    Type: Application
    Filed: March 3, 2008
    Publication date: November 20, 2008
    Inventors: Avi Tovi, Chaim Eidelman, Shimon Shushan, Shai Elster, Alon Hagi, Alexander Ivchenko, Gabriel-Marcus Butilca, Gil Zaoui, Eleonora Alterman, Leah Bar-Oz
  • Methods for the production of peptide derivatives
    Publication number: 20060276626
    Abstract: The invention relates to methods for the preparation of peptides which are a C-terminal amide derivatives by a combination of solid-phase synthesis and post assembly solution phase synthesis. The peptides which are a C-terminal amide derivatives are further converted to peptide acetates. The invention also relates to pure peptide acetates and to protected peptide precursors.
    Type: Application
    Filed: May 2, 2006
    Publication date: December 7, 2006
    Inventors: Avi Tovi, Chaim Eidelman, Shimon Shushan, Shai Elster, Hagi Alon, Alexander Ivchenko, Gabriel-Marcus Butilca, Gil Zaovi, Eleonora Alterman, Leah Bar-Oz, Tehila Gadi