Patents by Inventor Eleonora PEERANI

Eleonora PEERANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF FORMING PATIENT-DERIVED 3D CELL CULTURES FOR TRACKING LIVE IMMUNE-TUMOR INTERACTIONS
    Publication number: 20260056187
    Abstract: A method of forming a three-dimensional cell culture includes obtaining a tissue sample and a matched blood sample from a patient, isolating and staining tissue-derived cells, isolating and staining immune cells, culturing the tissue-derived cells in a hydrogel, and adding at least a portion of the immune cells to the hydrogel less than 24 hours later. The method mimics an in vivo tumor-immune environment and permits analysis of tumor-immune, immune-immune, and tumor-tumor cell interactions.
    Type: Application
    Filed: August 16, 2023
    Publication date: February 26, 2026
    Inventors: Jay KEARNEY, Gastón Agustín PRIMO, Eleonora PEERANI, Duleeka RANATUNGA, Thomas David Laurent RICHARDSON, Keqian NAN, Francesco IORI
  • Treatment efficacy prediction systems and methods
    Patent number: 11893733
    Abstract: Systems and methods for predicting a patient response to various agents and/or combinations of agents using ex vivo dosing and imaging are disclosed. In one example, a method of determining treatment efficacy includes analyzing a solid cell culture over time, e.g., first and second responses to a solid cell culture to respective treatments may be compared to determine a treatment efficacy of each treatment. Systems and methods for applying the treatments to the cell culture and analyzing the cell culture and efficacy are disclosed.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: February 6, 2024
    Assignee: OUROTECH, INC.
    Inventors: Duleeka Nimantha Bandara Ranatunga, Eleonora Peerani, Gastón Agustín Primo, Zhi Yuan Lin, Sacha Hu, Aston Martin Crawley
  • Treatment efficacy prediction systems and methods
    Patent number: 11847780
    Abstract: Systems and methods for predicting a patient response to various agents and/or combinations of agents using ex vivo dosing and imaging are disclosed. In one example, a method of determining treatment efficacy includes analyzing a solid cell culture over time, e.g., first and second responses to a solid cell culture to respective treatments may be compared to determine a treatment efficacy of each treatment. Systems and methods for applying the treatments to the cell culture and analyzing the cell culture and efficacy are disclosed.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: December 19, 2023
    Assignee: OUROTECH, INC.
    Inventors: Duleeka Nimantha Bandara Ranatunga, Eleonora Peerani, Gastón Agustín Primo, Zhi Yuan Lin, Sacha Hu, Aston Martin Crawley
  • TREATMENT EFFICACY PREDICTION SYSTEMS AND METHODS
    Publication number: 20230010963
    Abstract: Systems and methods for predicting a patient response to various agents and/or combinations of agents using ex vivo dosing and imaging are disclosed. In one example, a method of determining treatment efficacy includes analyzing a solid cell culture over time, e.g., first and second responses to a solid cell culture to respective treatments may be compared to determine a treatment efficacy of each treatment. Systems and methods for applying the treatments to the cell culture and analyzing the cell culture and efficacy are disclosed.
    Type: Application
    Filed: October 26, 2021
    Publication date: January 12, 2023
    Inventors: Duleeka Nimantha Bandara RANATUNGA, Eleonora PEERANI, Gastón Agustín PRIMO, Zhi Yuan LIN, Sacha HU, Aston Martin CRAWLEY
  • METHOD OF FORMING SOLID CELL CULTURES
    Publication number: 20230008421
    Abstract: Systems and methods for predicting a patient response to various agents and/or combinations of agents using ex vivo dosing and imaging are disclosed.
    Type: Application
    Filed: October 26, 2021
    Publication date: January 12, 2023
    Inventors: Duleeka Nimantha Bandara RANATUNGA, Eleonora PEERANI, Gastón Agustín PRIMO, Zhi Yuan LIN, Sacha HU, Aston Martin CRAWLEY