Patents by Inventor Eleonora Romagnoli

Eleonora Romagnoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis
    Patent number: 5608084
    Abstract: Lactones of formula ##STR1## and their pharmacologically acceptable salts endowed with antioxiding and hypolipidaemic properties and that show the capability to prevent and/or to delay the oxidative modification of the lipoproteins by competing with the chain of propagation of the lipidic peroxidation by means of an effective scavenging of the peroxylic radicals. The compounds object of the present invention are useful in the treatment of the atherosclerosis and of many correlated vascular pathologies, like ischaemic cardiopathies (angina pectoris and myocardial infarction), cerebral thrombosis and peripheral arteriopathies, because the high plasma levels of lipids and the oxidative modifications of the low density lipoproteins (LDL) represent crucial events in the pathogenesis of the atherosclerosis.
    Type: Grant
    Filed: November 13, 1995
    Date of Patent: March 4, 1997
    Assignee: Alfa Wassermann S.p.A.
    Inventors: Goffredo Rosini, Claudia Baldazzi, Eleonora Romagnoli, Stefano Saguatti, Silvano Piani