Patents by Inventor Elfrida Benjamin

Elfrida Benjamin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD TO PREDICT RESPONSE TO PHARMACOLOGICAL CHAPERONE TREATMENT OF DISEASES
    Publication number: 20170003301
    Abstract: The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining ?-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of ?-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
    Type: Application
    Filed: September 19, 2016
    Publication date: January 5, 2017
    Applicant: AMICUS THERAPEUTICS
    Inventors: Elfrida BENJAMIN, Hung V. Do, Xiaoyang Wu, John Flanagan, Brandon Wustman
  • METHOD TO PREDICT RESPONSE TO PHARMACOLOGICAL CHAPERONE TREATMENT OF DISEASES
    Publication number: 20150342940
    Abstract: The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining ?-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of ?-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
    Type: Application
    Filed: June 5, 2015
    Publication date: December 3, 2015
    Applicant: AMICUS THERAPEUTICS
    Inventors: Elfrida BENJAMIN, Hung V. Do, Xiaoyang Wu, John Flanagan, Brandon Wustman
  • Method to predict response to pharmacological chaperone treatment of diseases
    Patent number: 9095584
    Abstract: The present invention provides methods to determine whether a patient with a lysosomal storage disorder win benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining ?-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of ?-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: August 4, 2015
    Assignee: AMICUS THERAPEUTICS, INC.
    Inventors: Elfrida Benjamin, Hung V. Do, Xiaoyang Wu, John Flanagan, Brandon Wustman
  • METHOD TO PREDICT RESPONSE TO PHARMACOLOGICAL CHAPERONE TREATMENT OF DISEASES
    Publication number: 20140206721
    Abstract: The present invention provides methods to determine whether a patient with a lysosomal storage disorder win benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining ?-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of ?-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
    Type: Application
    Filed: October 15, 2013
    Publication date: July 24, 2014
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Elfrida Benjamin, Hung V. Do, Xiaoyang Wu, John Flanagan, Brandon Wustman
  • Method to predict response to pharmacological chaperone treatment of diseases
    Patent number: 8592362
    Abstract: The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining ?-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of ?-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: November 26, 2013
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Elfrida Benjamin, Hung V. Do, Xiaoyang Wu, John Flanagan, Brandon Wustman
  • Periodic acid-schiff staining with detection in the infrared range
    Patent number: 8283180
    Abstract: Provided is a method of detecting the presence and quantitating the amount of glycogen from a biological sample. This method employs PAS staining with detection in the infrared range.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: October 9, 2012
    Assignee: Amicus Therapeutics, Inc.
    Inventor: Elfrida Benjamin
  • METHOD TO PREDICT RESPONSE TO PHARMACOLOGICAL CHAPERONE TREATMENT OF DISEASES
    Publication number: 20110212996
    Abstract: The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining ?-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of ?-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
    Type: Application
    Filed: August 12, 2010
    Publication date: September 1, 2011
    Applicant: Amicus Therapeutics, Inc.
    Inventors: Elfrida Benjamin, Hung V. Do, Xiaoyang Wu, John Flanagan, Brandon Wustman
  • METHOD TO PREDICT RESPONSE TO PHARMACOLOGICAL CHAPERONE TREATMENT OF DISEASES
    Publication number: 20110152319
    Abstract: The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining ?-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of ?-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
    Type: Application
    Filed: August 20, 2010
    Publication date: June 23, 2011
    Applicant: Amicus Therapeutics, Inc.
    Inventors: Elfrida Benjamin, Hung V. Do, Xiaoyang Wu, John Flanagan, Brandon Wustman
  • PERIODIC ACID-SCHIFF STAINING WITH DETECTION IN THE INFRARED RANGE
    Publication number: 20100178667
    Abstract: Provided is a method of detecting the presence and quantitating the amount of glycogen from a biological sample. This method employs PAS staining with detection in the infrared range.
    Type: Application
    Filed: April 11, 2008
    Publication date: July 15, 2010
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventor: Elfrida Benjamin
  • 4-Pyrimidinamine derivatives, pharmaceutical compositions and related methods
    Publication number: 20050203092
    Abstract: This invention provides novel neuroprotective 4-pyrimidineamine derivatives and neuroprotective pharmaceutical compositions comprising 4-pyrimidinamines. This invention also provides methods of using these compositions to prevent ischemic cell death, particularly neuronal cell death, and reduce the likelihood of neuronal cell death in a subject due to a traumatic event. Finally, this invention provides an apparatus for administering to a subject the instant pharmaceutical compositions.
    Type: Application
    Filed: November 12, 2004
    Publication date: September 15, 2005
    Inventors: Elfrida Benjamin, Frank Brown, Robert Zivin, Michael McMillan, Zhong Zhong, Allen Reitz, Tina Ross