Patents by Inventor Elham Gazaleen-Mariee

Elham Gazaleen-Mariee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitric oxide donors and uses thereof
    Patent number: 7968575
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Grant
    Filed: May 5, 2005
    Date of Patent: June 28, 2011
    Assignee: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors having alkyl substituent(s) and uses thereof
    Patent number: 7579477
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: August 25, 2009
    Assignee: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors capable of releasing two or more nitric oxide molecules and uses thereof
    Patent number: 7498445
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: March 3, 2009
    Assignee: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof
    Patent number: 7368577
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: May 6, 2008
    Assignee: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors having acyl substituent(s) and uses thereof
    Patent number: 7332513
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: February 19, 2008
    Assignee: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors having at least two thiazole moieties and uses thereof
    Patent number: 7189750
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: March 13, 2007
    Assignee: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Nitric oxide donors and uses thereof
    Publication number: 20070021382
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Application
    Filed: May 5, 2005
    Publication date: January 25, 2007
    Applicant: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors having at least two thiazole moieties and uses thereof
    Publication number: 20060183912
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Application
    Filed: November 4, 2005
    Publication date: August 17, 2006
    Applicant: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors having acyl substuent(s) and uses thereof
    Publication number: 20060183913
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Application
    Filed: November 4, 2005
    Publication date: August 17, 2006
    Applicant: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof
    Publication number: 20060183718
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Application
    Filed: November 4, 2005
    Publication date: August 17, 2006
    Applicant: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors having alkyl substuent(s) and uses thereof
    Publication number: 20060069138
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Application
    Filed: November 4, 2005
    Publication date: March 30, 2006
    Applicant: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
  • Thiazole-based nitric oxide donors capable of releasing two or more nitric oxide molecules and uses thereof
    Publication number: 20060069139
    Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
    Type: Application
    Filed: November 4, 2005
    Publication date: March 30, 2006
    Applicant: Renopharm Ltd.
    Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh