Abstract: A drug delivery system includes a container comprising a luer compartment and a fluid compartment, a luer fitting arranged within the luer compartment and in fluidic communication with the fluid compartment, and a dispenser in fluidic communication with the fluid compartment. A method of aseptically transferring a drug to such a drug delivery system may include providing a vial comprising the drug to be transferred, withdrawing a volume of the drug from the vial with a syringe, coupling the syringe to a drug delivery system via the luer fitting, transferring the drug from the syringe to the drug delivery system, and decoupling the syringe from the drug delivery system.

Abstract: Drug delivery safety devices having trigger activation systems activated by pressure against the skin of a patient and which automatically shield the needle after withdrawing the needle from the skin of the patient.

Abstract: Drug delivery safety devices having trigger activation systems activated by pressure against the skin of a patient and which automatically shield the needle after withdrawing the needle from the skin of the patient.

Abstract: Provided herein are needle assemblies for intravitreal injection of an implant into an eye of a patient through an unsheathed state and a sheathed state. Such needle assemblies are precise and accurate for proper treatment and prevent further damage to the eye.

Abstract: Provided herein are needle assemblies for intravitreal injection of an (e.g., one or more) implant(s) into an eye of a patient through an unsheathed state and a sheathed state. Such needle assemblies are precise and accurate for proper treatment and prevent further damage to the eye.

Abstract: Provided herein are needle assemblies for intravitreal injection of an implant into an eye of a patient through an unsheathed state and a sheathed state. Such needle assemblies are precise and accurate for proper treatment and prevent further damage to the eye.

Abstract: A safety needle device is disclosed having a housing configured to couple to a syringe, the housing having a proximal end, a distal end, and a housing body. A needle hub is disposed on the proximal end of the housing and a needle cannula is attached to the needle hub. The device having a retractable sheath configured to move between an initial position, a retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula. The safety needle device may include an activation latch, a lockout latch, a tether and a spring element to bias the retractable sheath to an extended state to cover the distal end of the needle cannula upon completion of an injection. The safety needle device may include a slider element disposed above an activation latch. A method of drug delivery is also disclosed.

Abstract: Packaging for safety needle devices are described herein. Such packaging can include hard packaging for safety needle devices. Such packaging can include a cavity or recess in a compartment of the packaging to house an activation element of a safety needle device to prevent accidental activation of the safety needle device prior to use by the user. Such packaging can include a cavity or recess in a safety needle device to house an activation element located on the inside surface of the compartment of the packaging to prevent accidental activation of the safety needle device prior to use by the user.

Abstract: A safety needle device is disclosed comprising a hub, needle cannula, housing, tether, retractable sleeve, locking member and spring element. The tether is slidably disposed in the housing, the tether having a slot with an enlarged first guide path and a narrowed second guide path extending distally from the enlarged first guide path. The retractable sleeve is configured to move between an initial position, retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula.

Abstract: Low-profile fluid injection systems and methods for injecting fluid into a tumor within a body comprising an elongate member, a plurality of fluid delivery members, and a plurality of fluid reservoirs. Each of the plurality of fluid reservoirs may be fluidly coupled to a single of fluid delivery lumen of a single fluid delivery member such that each of the fluid delivery members is fluidly independent of every other fluid delivery member. The plurality of fluid delivery members may be configured to extend out of a distal end of the elongate member into the tumor when the system is positioned in the body of a patient. A fluid delivery mechanism may be operably coupled to the plurality of fluid reservoirs in order to deliver fluids from the plurality of fluid reservoirs to the plurality of fluid delivery members and inject the fluids into the tumor.

Abstract: Provided herein are needle assemblies for intravitreal injection of an implant into an eye of a patient through an unsheathed state and a sheathed state. Such needle assemblies are precise and accurate for proper treatment and prevent further damage to the eye.

Abstract: Drug delivery safety devices comprise a safety needle device comprising a needle hub, a needle cannula, and a safety feature; and a cap comprising a cap body having a proximal end attached to the safety needle device and a distal end having an access opening that is in fluid communication with the needle cannula. The safety needle device allow for an integrated device for both filling and injection that do not interfere with passive safety features. The caps may have a fill feature that engages with a safety feature of the safety needle device to keep it in a fill state.

Abstract: Drug delivery safety devices having trigger activation systems activated by pressure against the skin of a patient and which automatically shield the needle after withdrawing the needle from the skin of the patient.

Abstract: Drug delivery safety devices having trigger activation systems activated by pressure against the skin of a patient and which automatically shield the needle after withdrawing the needle from the skin of the patient.

Abstract: A safety needle device is disclosed having a hub, needle cannula, housing, tether, retractable sleeve, locking member and spring element. The tether is movably disposed in the housing, the tether having a slot with an enlarged first guide path and a narrowed second guide path extending distally from the enlarged first guide path. The retractable sleeve is configured to move from an initial position to partially expose a distal tip of the needle cannula, a retracted position to fully exposes the needle cannula, and an extended position to fully cover the distal tip of the needle cannula. The proximal movement of one or more protrusions on the retractable sleeve, rotates the tether to move the at least one or more protrusions from the enlarged first guide path of the tether to the narrowed second guide path of the tether, this rotation activating the device.

Abstract: A safety needle device is disclosed having a hub, needle cannula, housing, tether, retractable sleeve, locking member and spring element. The tether is movably disposed in the housing, the tether having a slot with an enlarged first guide path and a narrowed second guide path extending distally from the enlarged first guide path. The retractable sleeve is configured to move from an initial position to partially expose a distal tip of the needle cannula, a retracted position to fully exposes the needle cannula, and an extended position to fully cover the distal tip of the needle cannula. The proximal movement of one or more protrusions on the retractable sleeve, rotates the tether to move the at least one or more protrusions from the enlarged first guide path of the tether to the narrowed second guide path of the tether, this rotation activating the device.

Abstract: A safety needle device is disclosed having a housing configured to couple to a syringe, the housing having a proximal end, a distal end, and a housing body. A needle hub is disposed on the proximal end of the housing and a needle cannula is attached to the needle hub. The device having a retractable sheath configured to move between an initial position, a retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula. The safety needle device may include an activation latch, a lockout latch, a tether and a spring element to bias the retractable sheath to an extended state to cover the distal end of the needle cannula upon completion of an injection. The safety needle device may include a slider element disposed above an activation latch. A method of drug delivery is also disclosed.

Abstract: A safety needle device is disclosed having a housing configured to couple to a syringe, the housing having a proximal end, a distal end, and a housing body. A needle hub is disposed on the proximal end of the housing and a needle cannula is attached to the needle hub. The device having a retractable sheath configured to move between an initial position, a retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula. The safety needle device may include an activation latch, a lockout latch, a tether and a spring element to bias the retractable sheath to an extended state to cover the distal end of the needle cannula upon completion of an injection. The safety needle device may include a slider element disposed above an activation latch. A method of drug delivery is also disclosed.

Abstract: A catheter insertion device which employs back-and-forth longitudinal axial movement to advance the catheter by the cooperative interface of an incline ramp and a decline ramp with a split gripping mechanism is described.

Abstract: A dispensing device, comprising: a piston-cylinder assembly, the assembly comprising an outlet in fluid communication with a one-way valve and an inlet in fluidic communication with a valve assembly; the one-way valve configured to dispense a liquid from a medicament container, the valve assembly fluidically coupled to the one-way valve, the valve assembly having at least one cannula and at least one flow control member; the piston configured to draw an amount of fluid through the valve assembly and inlet into the cylinder, and to expel the amount of liquid through the one-way valve; and an actuator assembly coupled to and biasing the piston with stored energy.