Patents by Inventor Eli Glezer

Eli Glezer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10954551
    Abstract: Methods, systems, and reagents for real-time single molecule sequencing of nucleic acids, particularly long DNA molecules, is described. Preferably, such methods and systems combine FRET (Förster Resonance Energy Transfer)-based proximity sensing of labeled nucleotides in or near a DNA polymerase's active site with FRET-based monitoring of the conformational changes in the polymerase that occur during nucleotide incorporation.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: March 23, 2021
    Assignee: Singular Genomics Systems, Inc.
    Inventor: Eli Glezer
  • Publication number: 20210033523
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adopted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: August 18, 2020
    Publication date: February 4, 2021
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Patent number: 10782227
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: September 22, 2020
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Publication number: 20200240903
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: April 10, 2020
    Publication date: July 30, 2020
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Publication number: 20200102609
    Abstract: The present disclosure provides improved nucleic acid sequencing-by-synthesis (SBS) methods, related kits and reagents, and systems for performing such methods using such kits and reagents.
    Type: Application
    Filed: March 6, 2018
    Publication date: April 2, 2020
    Inventors: Eli GLEZER, Andrew SPAVENTA, David BARKER
  • Publication number: 20200080065
    Abstract: Provided herein are modified Archaeal family B polymerases derived from the Archaeal microorganism Pyrococcus abyssi that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.
    Type: Application
    Filed: September 11, 2019
    Publication date: March 12, 2020
    Inventors: Carl W. FULLER, Eli GLEZER, Andrew SPAVENTA, Souad NAJI
  • Patent number: 10539501
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: January 21, 2020
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Patent number: 10459108
    Abstract: The invention relates to measuring and generating electrical fields downhole. In one embodiment a system is provided that includes an amplifier connected to a first electrode in electrical contact with the Earth via an operative capacitive coupling. An additional electrode and amplifier are disposed in the borehole opposite the first electrode and constitute a first pair of electrodes spaced in a direction orthogonal to the axis. A second electrode is part of a group of counter electrodes spaced from each other and disposed outside the borehole. The first pair of electrodes and the amplifiers are configured to be one of a source that generates an electrical field in a direction substantially orthogonal to the axis of the borehole and a sensor that measures an electric field substantially orthogonal to the axis of the borehole.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: October 29, 2019
    Assignee: GroundMetrics, Inc.
    Inventors: Andrew Hibbs, Eli Glezer
  • Publication number: 20180299576
    Abstract: The invention relates to measuring and generating electrical fields downhole. In one embodiment a system is provided that includes an amplifier connected to a first electrode in electrical contact with the Earth via an operative capacitive coupling. An additional electrode and amplifier are disposed in the borehole opposite the first electrode and constitute a first pair of electrodes spaced in a direction orthogonal to the axis. A second electrode is part of a group of counter electrodes spaced from each other and disposed outside the borehole. The first pair of electrodes and the amplifiers are configured to be one of a source that generates an electrical field in a direction substantially orthogonal to the axis of the borehole and a sensor that measures an electric field substantially orthogonal to the axis of the borehole.
    Type: Application
    Filed: June 26, 2018
    Publication date: October 18, 2018
    Inventors: Andrew HIBBS, Eli GLEZER
  • Publication number: 20180258472
    Abstract: Methods, systems, and reagents for real-time single molecule sequencing of nucleic acids, particularly long DNA molecules, is described. Preferably, such methods and systems combine FRET (Förster Resonance Energy Transfer)-based proximity sensing of labeled nucleotides in or near a DNA polymerase's active site with FRET-based monitoring of the conformational changes in the polymerase that occur during nucleotide incorporation.
    Type: Application
    Filed: March 7, 2018
    Publication date: September 13, 2018
    Inventor: Eli Glezer
  • Patent number: 10036825
    Abstract: The invention relates to measuring and generating electrical fields downhole. In one embodiment a system is provided that includes an amplifier connected to a first electrode in electrical contact with the Earth via an operative capacitive coupling. An additional electrode and amplifier are disposed in the borehole opposite the first electrode and constitute a first pair of electrodes spaced in a direction orthogonal to the axis. A second electrode is part of a group of counter electrodes spaced from each other and disposed outside the borehole. The first pair of electrodes and the amplifiers are configured to be one of a source that generates an electrical field in a direction substantially orthogonal to the axis of the borehole and a sensor that measures an electric field substantially orthogonal to the axis of the borehole.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: July 31, 2018
    Assignee: GroundMetrics, Inc.
    Inventors: Andrew Hibbs, Eli Glezer
  • Publication number: 20170370827
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: May 5, 2017
    Publication date: December 28, 2017
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Patent number: 9664613
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: November 11, 2010
    Date of Patent: May 30, 2017
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Publication number: 20150160364
    Abstract: The invention relates to measuring and generating electrical fields downhole. In one embodiment a system is provided that includes a first electrical conductor within a borehole and in electrical contact with the Earth. An amplifier is connected to the first electrical conductor and a second conductor completes an electrical circuit between the conductors such that the electrical field is oriented in a direction substantially orthogonal to the axis of the borehole.
    Type: Application
    Filed: May 22, 2012
    Publication date: June 11, 2015
    Applicant: Groundmetrics, Inc.
    Inventors: Andrew Hibbs, Eli Glezer
  • Patent number: 9034263
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: May 19, 2015
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Patent number: 8808627
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: November 11, 2010
    Date of Patent: August 19, 2014
    Assignee: Meso Scale Technologies, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Patent number: 8790578
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: July 29, 2014
    Assignee: Meso Scale Technologies, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Patent number: 8361385
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: January 29, 2013
    Assignee: Meso Scale Technologies, LLC
    Inventors: Eli Glezer, Kent Johnson, Bandele Jeffrey-Coker, Alan Kishbaugh, Charles Clinton
  • Publication number: 20120190590
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: April 4, 2012
    Publication date: July 26, 2012
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Publication number: 20120190591
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: April 4, 2012
    Publication date: July 26, 2012
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer