Patents by Inventor Eli Hatchwell

Eli Hatchwell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for discovery of causative mutations in genetic disorders
    Patent number: 10059997
    Abstract: The compositions and methods provided herein allow for identification of causative genetic biomarkers for a disease condition or drug response.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: August 28, 2018
    Assignee: POPULATION BIO, INC.
    Inventors: Eli Hatchwell, Peggy S. Eis
  • METHODS FOR ASSESSING RISK OF DEVELOPING A VIRAL DISEASE USING A GENETIC TEST
    Publication number: 20180223360
    Abstract: This document provides methods and materials related to treating a disease. For example, this document provides methods for treating a subject's disease based on identifying the risk of progressive multifocal leukoencephalopathy PML using a genetic test.
    Type: Application
    Filed: June 30, 2017
    Publication date: August 9, 2018
    Inventors: Eli HATCHWELL, Peggy S. EIS, Edward B. SMITH, III, Yassine TAOUFIK
  • Methods for detecting a genetic variation in subjects with parkinsonism
    Patent number: 9976180
    Abstract: This document provides methods and materials related to genetic variations of neurological disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Parkinson's disease.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: May 22, 2018
    Assignee: POPULATION BIO, INC.
    Inventors: Eli Hatchwell, Peggy S. Eis
  • METHODS AND COMPOSITIONS FOR SCREENING AND TREATING DEVELOPMENTAL DISORDERS
    Publication number: 20180073076
    Abstract: This document provides methods and materials related to genetic variations of developmental disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Autism Spectrum Disorder.
    Type: Application
    Filed: September 28, 2016
    Publication date: March 15, 2018
    Inventors: Eli HATCHWELL, Peggy S. EIS
  • METHODS AND COMPOSITIONS FOR INHIBITING AND TREATING NEUROLOGICAL CONDITIONS
    Publication number: 20170253930
    Abstract: This document provides methods and materials related to treating subjects having specific genetic variations associated with neurological disorders such as Parkinson's disease.
    Type: Application
    Filed: September 4, 2015
    Publication date: September 7, 2017
    Applicant: POPULATION BIO, INC.
    Inventors: Eli HATCHWELL, Peggy EIS
  • EVALUATING GENETIC DISORDERS
    Publication number: 20160019336
    Abstract: The present invention relates to genetic analysis and evaluation utilizing copy-number variants or polymorphisms. The methods utilize array comparative genomic hybridization and PCR assays to identify the significance of copy number variations in a human, non-human animal, and plant subject or subject group.
    Type: Application
    Filed: July 22, 2015
    Publication date: January 21, 2016
    Inventors: James CHINITZ, Eli HATCHWELL
  • METHODS AND COMPOSITIONS FOR DIAGNOSING, PROGNOSING, AND TREATING ENDOMETRIOSIS
    Publication number: 20150132295
    Abstract: This document provides methods and materials related to genetic variations associated with endometriosis. For example, this document provides methods for using such genetic variations to assess risk of, or susceptibility of developing or diagnosing endometriosis.
    Type: Application
    Filed: November 11, 2014
    Publication date: May 14, 2015
    Inventors: ELI HATCHWELL, PEGGY S. EIS
  • COMPOSITIONS AND METHODS FOR DISCOVERY OF CAUSATIVE MUTATIONS IN GENETIC DISORDERS
    Publication number: 20150051086
    Abstract: The compositions and methods provided herein allow for identification of causative genetic biomarkers for a disease condition or drug response.
    Type: Application
    Filed: August 1, 2014
    Publication date: February 19, 2015
    Inventors: Eli HATCHWELL, Peggy S. EIS
  • Compositions and methods for discovery of causative mutations in genetic disorders
    Patent number: 8862410
    Abstract: The compositions and methods provided herein allow for identification of causative genetic biomarkers for a disease condition or drug response.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: October 14, 2014
    Assignee: Population Diagnostics, Inc.
    Inventors: Eli Hatchwell, Peggy S. Eis
  • Methods And Compositions For Screening And Treating Developmental Disorders
    Publication number: 20140161721
    Abstract: This document provides methods and materials related to genetic variations of developmental disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Autism Spectrum Disorder.
    Type: Application
    Filed: February 8, 2013
    Publication date: June 12, 2014
    Inventors: Eli Hatchwell, Peggy S. Eis, Stephen Scherer, Aparna Prasad
  • Methods and Compositions for Diagnosing, Prognosing, and Treating Neurological Conditions
    Publication number: 20140162933
    Abstract: This document provides methods and materials related to genetic variations of neurological disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Parkinson's disease.
    Type: Application
    Filed: September 13, 2013
    Publication date: June 12, 2014
    Inventors: Eli Hatchwell, Peggy S. Eis
  • METHODS AND COMPOSITIONS FOR SCREENING AND TREATING DEVELOPMENTAL DISORDERS
    Publication number: 20140162894
    Abstract: This document provides methods and materials related to genetic variations of developmental disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Autism Spectrum Disorder.
    Type: Application
    Filed: September 27, 2013
    Publication date: June 12, 2014
    Applicant: Population Diagnostics, Inc.
    Inventors: Eli Hatchwell, Peggy S. Eis
  • METHODS AND COMPOSITIONS FOR DIAGNOSING, PROGNOSING, AND TREATING NEUROLOGICAL CONDITIONS
    Publication number: 20140155271
    Abstract: This document provides methods and materials related to genetic variations of neurological disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Parkinson's disease.
    Type: Application
    Filed: November 2, 2012
    Publication date: June 5, 2014
    Applicants: Population Diagnostics, Inc., The Research Foundation of State of University of New York
    Inventors: ELI HATCHWELL, PEGGY S. EIS
  • EVALUATING GENETIC DISORDERS
    Publication number: 20140088882
    Abstract: The present invention relates to genetic analysis and evaluation utilizing copy-number variants or polymorphisms. The methods utilize array comparative genomic hybridization and PCR assays to identify the significance of copy number variations in a subject or subject group.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 27, 2014
    Applicant: Population Diagnostics, Inc.
    Inventors: James CHINITZ, Eli HATCHWELL
  • Evaluating genetic disorders
    Patent number: 8655599
    Abstract: The present invention relates to genetic analysis and evaluation utilizing copy-number variants or polymorphisms. The methods utilize array comparative genomic hybridization and PCR assays to identify the significance of copy number variations in a subject or subject group.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: February 18, 2014
    Assignee: Population Diagnostics, Inc.
    Inventors: James Chinitz, Eli Hatchwell
  • Methods for determining cytosine methylation in DNA and uses thereof
    Patent number: 8642294
    Abstract: Methods are described for determining the pattern of cytosine methylation in a DNA specimen, where the methods involve comparing the amount of DNA fragments generated by a methylation-sensitive restriction enzyme with the amount of DNA fragments generated by a methylation-insensitive isoschizomer of the methylation-sensitive restriction enzyme.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: February 4, 2014
    Assignees: Albert Einstein College of Medicine of Yeshiva University, The Research Foundation State University of New York
    Inventors: John M. Greally, Eli Hatchwell
  • Methods Employing McrA to Detect 5-Methyl Cytosine
    Publication number: 20120219942
    Abstract: The invention provides methods for using the rMcrA protein, and derivatives thereof, for direct or semi-direct determination of the methylation status of CpG dinucleotides in methyl-CpG island sequences of interest.
    Type: Application
    Filed: December 13, 2011
    Publication date: August 30, 2012
    Applicant: Brookhaven Science Associates, LLC
    Inventors: John J. Dunn, Eli Hatchwell
  • COMPOSITIONS AND METHODS FOR DISCOVERY OF CAUSATIVE MUTATIONS IN GENETIC DISORDERS
    Publication number: 20120059594
    Abstract: The compositions and methods provided herein allow for identification of causative genetic biomarkers for a disease condition or drug response.
    Type: Application
    Filed: August 2, 2011
    Publication date: March 8, 2012
    Applicant: Population Diagnostics, Inc.
    Inventors: Eli Hatchwell, Peggy S. Eis
  • EVALUATING GENETIC DISORDERS
    Publication number: 20110264376
    Abstract: The present invention relates to genetic analysis and evaluation utilizing copy-number variants or polymorphisms. The methods utilize array comparative genomic hybridization and PCR assays to identify the significance of copy number variations in a subject or subject group.
    Type: Application
    Filed: April 27, 2011
    Publication date: October 27, 2011
    Applicant: POPULATION DIAGNOSTICS, INC.
    Inventors: James CHINITZ, Eli Hatchwell
  • Evaluating genetic disorders
    Patent number: 7957913
    Abstract: The present invention relates to genetic analysis and evaluation utilizing copy-number variants or polymorphisms. The methods utilize array comparative genomic hybridization and PCR assays to identify the significance of copy number variations in a subject or subject group.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: June 7, 2011
    Assignee: Population Diagnostics, Inc.
    Inventors: James Chinitz, Eli Hatchwell