Patents by Inventor Eli Hazum

Eli Hazum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLUTAMATE OXALOACETATE TRANSAMINASE 1 (GOT1), PREPARATIONS AND METHODS OF GENERATING SAME AND USES THEREOF
    Publication number: 20180071369
    Abstract: A protein preparation comprising Glutamate Oxaloacetate Transaminase 1 (GOT1) polypeptide molecules is disclosed, the GOT1 being identical in its sequence to that present in human serum. 100% of the GOT1 polypeptide molecules of the preparation have an alanine at position 1 of the GOT1 polypeptide. The GOT1 polypeptide molecules constitute at least 95% of the proteins in the preparation. Methods of generating same and uses thereof are also disclosed.
    Type: Application
    Filed: March 31, 2016
    Publication date: March 15, 2018
    Inventors: David MIRELMAN, Aharon RABINKOV, Angela RUBAN, Ghil JONA, Eli HAZUM, Vladas BUMELIS, Nerijus MAKAUSKAS, Saule SUDZIUVIENE, Elena NARMONTAITE
  • ANTISENSE OLIGONUCLEOTIDES AGAINST ACETYLCHOLINESTERASE FOR TREATING INFLAMMATORY DISEASES
    Publication number: 20120196920
    Abstract: The present invention relates to novel uses of antisense oligolucleotides targeted to the coding region of acetylcholinesterase (AChE) for treating inflammatory disorders other than inflammatory disorders of the central nervous system or the peripheral nervous system innervating voluntary muscles. More particularly, the present invention relates to uses of antisense oligodexoynucleotides targeted to AChE mRNA for treating inflammatory disease of the gastroinstestinal tract including inflammatory bowel disease.
    Type: Application
    Filed: November 29, 2011
    Publication date: August 2, 2012
    Applicant: AMARIN PHARMA, INC.
    Inventors: Eli Hazum, Lior Carmon
  • ANTISENSE OLIGONUCLEOTIDES AGAINST ACETYLCHOLINESTERASE FOR TREATING INFLAMMATORY DISEASES
    Publication number: 20090275634
    Abstract: The present invention relates to novel uses of antisense oligonucleotides targeted to the coding region of acetylcholinesterase (AChE) for treating inflammatory disorders other than inflammatory disorders of the central nervous system or the peripheral nervous system innervating voluntary muscles. More particularly, the present invention relates to uses of antisense oligodexoynucleotides targeted to AChE mRNA for treating inflammatory disease of the gastrointestinal tract including inflammatory bowel disease.
    Type: Application
    Filed: March 29, 2007
    Publication date: November 5, 2009
    Applicant: AMARIN CORPORATION PLC
    Inventors: Eli Hazum, Lior Carmon
  • Intracoronary stents containing quinazolinone derivatives
    Patent number: 6159488
    Abstract: The invention provides an intracoronary stent coated with a quinazolinone derivative of formula (I), wherein n is 1 or 2, R.sub.1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy; R.sub.2 is a member of the group consisting of hydroxy, acetoxy and lower alkoxy, and R3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl, and physiologically acceptable salts thereof, for preventing restenosis after angioplasty.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: December 12, 2000
    Assignees: Agricultural Research Org. Ministry of Agriculture (Gov.), HadasitMedical Research Serv. & Devel. Ltd.
    Inventors: Arnon Nagler, Eli Hazum, Ehud Geller, Shimon Slavin, Israel Vlodavsky, Mark Pines