Patents by Inventor Eli J. Weinberg

Eli J. Weinberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic structures for biomedical applications
    Patent number: 10265698
    Abstract: Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: April 23, 2019
    Assignees: The Charles Stark Draper Laboratory, Inc., The Brigham and Women's Hospital, Inc., The Massachusetts Institute of Technology
    Inventors: Jeffrey T. Borenstein, Eli J. Weinberg, James C. Hsiao, Ahmad S. Khalil, Malinda M. Tupper, Guillermo Garcia-Cardena, Peter Mack, Sarah L. Tao
  • Systems and method for high-throughput testing
    Patent number: 10232336
    Abstract: The systems and methods described herein relate to a high-throughput flow apparatus. The apparatus is used with an array of wells, and is configured to impart a predetermined shear stress on cells cultured within each of the wells of the array of wells. The apparatus includes a plurality of mechanical tips. The plurality of mechanical tips each includes a head with a hemispheroid shape. The apparatus also includes a motor associated with at least one of plurality of mechanical tips. The motor is configured to drive the plurality of mechanical tips to impart the shear stress pattern in each of the wells.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: March 19, 2019
    Assignees: The Charles Stark Draper Laboratory, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Guillermo Garcia-Cardena, Peter Mack, Jeffrey T. Borenstein, Ahmad S. Khalil, Eli J. Weinberg, Jason O. Fiering, Ernest S. Kim, William J. Adams, Jr., Mitchell Hansberry, Stephen Bellio
  • MICROFLUIDIC STRUCTURES FOR BIOMEDICAL APPLICATIONS
    Publication number: 20160129440
    Abstract: Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.
    Type: Application
    Filed: November 6, 2015
    Publication date: May 12, 2016
    Inventors: Jeffrey T. Borenstein, Eli J. Weinberg, James C. Hsiao, Ahmad S. Khalil, Malinda M. Tupper, Guillermo Garcia-Cardena, Peter Mack, Sarah L. Tao
  • microfluidic structures for biomedical applications
    Patent number: 9181082
    Abstract: Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: November 10, 2015
    Assignees: The Charles Stark Draper Laboratory, Inc., Brigham and Women's Hospital, Inc.
    Inventors: Jeffrey T. Borenstein, Eli J. Weinberg, James C. Hsiao, Ahmad S. Khalil, Malinda M. Tupper, Guillermo Garcia-Cardena, Peter Mack, Sarah L. Tao
  • SYSTEMS AND METHOD FOR HIGH-THROUGHPUT TESTING
    Publication number: 20150126411
    Abstract: The systems and methods described herein relate to a high-throughput flow apparatus. The apparatus is used with an array of wells, and is configured to impart a predetermined shear stress on cells cultured within each of the wells of the array of wells. The apparatus includes a plurality of mechanical tips. The plurality of mechanical tips each includes a head with a hemispheroid shape. The apparatus also includes a motor associated with at least one of plurality of mechanical tips. The motor is configured to drive the plurality of mechanical tips to impart the shear stress pattern in each of the wells.
    Type: Application
    Filed: November 6, 2014
    Publication date: May 7, 2015
    Inventors: Guillermo Garcia-Cardena, Peter Mack, Jeffrey T. Borenstein, Ahmad S. Khalil, Eli J. Weinberg, Jason O. Fiering, Ernest S. Kim, William J. Adams, JR., Mitchell Hansberry, Stephen Bellio
  • High-throughput biological screening
    Patent number: 9006149
    Abstract: A high-throughput flow system includes an array of wells and a separate mechanical tip positioned within each well. Each mechanical tip is separately actuated to impart a shear stress pattern. A separate sleeve may be associated with each tip for maintaining a predetermined distance between the tip and a floor of the tip's corresponding well, with each tip being rotatable within its corresponding sleeve. Alternatively, a separate post may be associated with each tip for maintaining a predetermined distance between the tip and a floor of the tip's corresponding well, with each tip being rotatable about its corresponding post.
    Type: Grant
    Filed: January 14, 2010
    Date of Patent: April 14, 2015
    Assignees: The Charles Stark Draper Laboratory, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Guillermo Garcia-Cardena, Peter Mack, Jeffrey T. Borenstein, Ahmad S. Khalil, Eli J. Weinberg, Jason O. Fiering, Ernest S. Kim, William J. Adams, Jr.
  • FABRICATING MICROFLUIDIC STRUCTURES FOR BIOMEDICAL APPLICATIONS
    Publication number: 20130004386
    Abstract: Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.
    Type: Application
    Filed: September 10, 2012
    Publication date: January 3, 2013
    Inventors: Jeffrey T. Borenstein, Eli J. Weinberg, James C. Hsiao, Ahmad S. Khalil, Malinda M. Tupper, Guillermo Garcia-Cardena, Peter Mack, Sarah L. Tao
  • Method of fabricating microfluidic structures for biomedical applications
    Patent number: 8266791
    Abstract: Methods of fabricating microfluidic structures featuring substantially circular channels are provided. The methods involve (a) providing a patterned wafer comprising at least one exposed electrically conductive region and at least one exposed electrically insulating region; (b) electroplating an inverse channel portion with substantially semicircular cross section onto the wafer, thereby forming a first master mold; (c) employing the first master mold so as to emboss a channel portion in a first polymer sheet; and (d) aligning and bonding the first polymer sheet with a second polymer sheet having a corresponding channel portion such as to define a first channel with substantially circular cross section between the polymer sheets.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: September 18, 2012
    Assignees: The Charles Stark Draper Laboratory, Inc., Brigham and Women's Hospital, Inc.
    Inventors: Jeffrey T. Borenstein, Eli J. Weinberg, James Ching-Ming Hsiao, Ahmad S. Khalil, Malinda M. Tupper, Guillermo Garcia-Cardena, Peter Mack, Sarah L. Tao
  • High-Throughput Biological Screening
    Publication number: 20100323916
    Abstract: In one embodiment, a high-throughput flow system includes an array of wells and a separate mechanical tip positioned within each well. Each mechanical tip is separately actuated to impart a shear stress pattern.
    Type: Application
    Filed: January 14, 2010
    Publication date: December 23, 2010
    Inventors: Guillermo Garcia-Cardena, Peter Mack, Jeffrey T. Borenstein, Ahmad S. Khalil, Eli J. Weinberg, Jason O. Fiering, Ernest S. Kim, William J. Adam, JR.
  • Microfluidic Structures for Biomedical Applications
    Publication number: 20090181200
    Abstract: Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.
    Type: Application
    Filed: September 19, 2008
    Publication date: July 16, 2009
    Inventors: Jeffrey T. Borenstein, Eli J. Weinberg, James C. Hsiao, Ahmad S. Khalil, Malinda M. Tupper, Guillermo Garcia-Cardena, Peter Mack, Sarah L. Tao