Abstract: The present invention relates to a method for generating hypotheses automatically from graphical models built directly from data. The method of the present invention links three key scientific concepts to enable hypothesis generation from data driven hypothesis-models: including the use of information theory based measures to identify informative feature subsets within the data; the automatic generation of graphical models from the informative data subsets identified from step one; and the application of optimization methods to graphical models to enable hypothesis generation. The integration of these three concepts can enable scalable approaches to hypothesis generation from large, complex data environments. The use of graphical models as the model representation can allow prior knowledge to be effectively integrated into the modeling environment.

Abstract: The present invention relates to a method for generating hypotheses automatically from graphical models built directly from data. The method of the present invention links three key scientific concepts to enable hypothesis generation from data driven hypothesis-models: including the use of information theory based measures to identify informative feature subsets within the data; the automatic generation of graphical models from the informative data subsets identified from step one; and the application of optimization methods to graphical models to enable hypothesis generation. The integration of these three concepts can enable scalable approaches to hypothesis generation from large, complex data environments. The use of graphical models as the model representation can allow prior knowledge to be effectively integrated into the modeling environment.

Abstract: A system for the representation, editing, evaluation, and inference of graphical models is disclosed which can be used to construct and evaluate a graphical model or graphical network and to calculate inference values. An efficient method of updating graphical models is demonstrated, and provides the basis for an improved system for manipulation and evaluation of probabilistic models. The graphical network editor is useful in the construction of graphical modes such as Bayesian Networks. The graphical network and network graphical user interface (GUI) are used in conjunction with each other to model a system wherein failure probabilities and the current state of components are taken into account to monitor the health and progress of a system for an engineer or engineering software to evaluate and monitor.

Abstract: The present invention provides a means for performing scalable, computationally efficient and rapid simulations of complex or complex adaptive systems realized through the dynamic interaction of multiple modeling components to generate outputs suited to decision support, analysis and planning. In the context of disease modeling, these outputs can be used for analyzing the impact of disease and the potential value of the use of pharmaceutical and non-pharmaceutical interventions.