Patents by Inventor Eliahu Heidman

Eliahu Heidman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optical isomers
    Patent number: 4981858
    Abstract: The (+)-cis-, (-)-cis-, (+)-trans- and (-)-trans- forms of 2-methylspiro(1,3-oxathiolan-5,3')quinuclidine are prepared by optical resolution of each of the (.+-.)-cis- and (.+-.)-trans-isomers. These compounds find application in treating diseases of the central nervous system in mammals, especially diseases due to a deficiency in the central cholinergic system. Biological tests indicate that the (-)-cis-form, as well as the (.+-.)-cis-isomer, shows particular promise for treating senile dementia of Alzheimer's type.
    Type: Grant
    Filed: April 18, 1989
    Date of Patent: January 1, 1991
    Assignee: State of Israel, represented by the Prime Minister's Office, Israel Institute for Biological Research
    Inventors: Abraham Fisher, Ishal Karton, Eliahu Heidman, Yona Grunfeld, Aharon Levy