Abstract: The present disclosure provides compounds, compositions, and methods, wherein the compounds include a modified cholic acid or a cholic acid component and at least a second component in which the second component is conjugated to the modified cholic acid or cholic acid having the following structure: In certain instances, the conjugate compound provides reduced cytotoxicity, greater efficacy, and a more robust MOA (e.g., the entry into a cell is more facile or multiple modes of action occur) compared to the non-conjugated component alone. In certain instances, the second component such as biotin is covalently linked to the modified cholic acid or cholic acid.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: This invention relates to articles of manufacture containing liquid compositions of hypohalous acid or hypohalous acid salt for deactivating allergens and preventing diseases on hard surfaces, soft surfaces and in the air. The articles of manufacture contain usage instructions with health claims. This invention also includes methods of instructing the public and promoting the use of these compositions.

Abstract: This invention relates to methods of diluting hypochlorite and hypochlorous acid compositions with purified water to produce stable compositions. These compositions can be used to treat allergen containing surfaces, hard surfaces, food contact surfaces, hospital surfaces, food surfaces, kitchen surfaces, bathroom surfaces, human surfaces, animal surfaces, military equipment, transportation equipment, children's items, plant surfaces, seeds, outdoor surfaces, soft surfaces, air, wounds, and medical instruments.

Abstract: Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base.

Abstract: An improved cleaning composition adapted to clean a variety of hard surfaces. The improved cleaning composition includes a cationic biocide that includes biguanide compounds and/or quats.

Abstract: An improved cleaning composition adapted to clean a variety of hard surfaces. The improved cleaning composition includes a cationic biocide that includes biguanide compounds and/or quats.

Abstract: Provided is a demonstration apparatus comprising a top subassembly and a bottom subassembly. The top subassembly includes a reservoir adapted to contain a consumer product to be demonstrated. The consumer product has efficacy to produce a consumer-desired effect that is directly or indirectly observable. The bottom subassembly includes a vial containing a contaminant upon which the consumer product produces the consumer-desired effect. The top sub assembly and bottom subassembly are coupled to a reservoir seal element. Upon activation of the demonstration apparatus, the consumer product flows into the bottom subassembly and contacts the contaminant to produce the consumer-desired effect. Also provided, are a method of use for the demonstration apparatus and a kit containing the demonstration apparatus.

Abstract: Provided is sampling device and method for the detection of protein-containing substances. The sampling device includes a first reagent holder coupled to a second reagent holder by an activating member. Coupled to first reagent holder is a first reagent reservoir and coupled to second reagent holder is a second reagent reservoir. The first reagent reservoir is protected from the ambient environment by a first reagent protector and the second reagent reservoir is similarly protected from the ambient environment by a second reagent protector. After a sample has been obtained from the surface of a sampling object, the application of a sufficient activation force on the activating member places the first reagent reservoir in fluid communication with the second reagent reservoir.

Abstract: An improved cleaning composition adapted to clean a variety of hard surfaces. The improved cleaning composition includes a cationic biocide that includes biguanide compounds and/or quats.

Abstract: An improved cleaning composition and method adapted to clean a variety of hard surfaces. The improved cleaning composition and method includes the use of a cationic biocide that includes biguanide compounds and/or quats.

Abstract: This invention relates to methods of diluting hypochlorite and hypochlorous acid compositions to produce stable compositions. These compositions can be used to treat allergen containing surfaces, hard surfaces, food contact surfaces, hospital surfaces, food surfaces, kitchen surfaces, bathroom surfaces, human surfaces, animal surfaces, military equipment, transportation equipment, children's items, plant surfaces, seeds, outdoor surfaces, soft surfaces, air, wounds, and medical instruments.

Abstract: This invention relates to articles of manufacture containing liquid compositions of hypohalous acid or hypohalous acid salt for deactivating allergens and preventing diseases on hard surfaces, soft surfaces and in the air. The articles of manufacture contain usage instructions with health claims. This invention also includes methods of instructing the public and promoting the use of these compositions.

Abstract: This invention relates to a complete mold system that provides consumers with tools for understanding, detecting, removing and preventing mold. The complete mold system will provide consumers with one comprehensive resource for taking care of their mold problem anywhere in the home. In addition to specific tools for detecting, removing, inhibiting/delaying and preventing mold, educational materials will guide consumers in a step-by-step manner on how best to take care of their mold problem.

Abstract: The present invention relates to disinfecting wipes or pads that can be use to treat or clean glass or other glossy surfaces. The disinfecting wipes or pads do not depend upon quaternary ammonium compounds for disinfection, but instead depend upon relatively low solvent levels and basic pH or relatively high levels of sodium hydroxide or potassium hydroxide.