Patents by Inventor Elimelech Rochlin

Elimelech Rochlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sphingolipids' polyalkylamines conjugates
    Patent number: 7771711
    Abstract: The present invention concerns novel sphingolipid-polyalkylamines conjugates, a process for their preparation and pharmaceutical compositions comprising the same. In particular, the present invention concerns ceramide based polyalkylamine conjugates and its use as a capturing agent. A preferred ceramide polyalkylamine conjugate is a ceramide-spermine conjugate, more preferably, N-palmitoyl D-erythro sphingosyl-1-carbamoyl spermine.
    Type: Grant
    Filed: June 17, 2004
    Date of Patent: August 10, 2010
    Assignees: Yissum Research Development Company of The Hebrew University of Jerusalem, Biolab Ltd.
    Inventors: Yechezkel Barenholz, Dmitri Simberg, Elimelech Rochlin
  • Sphingomyelin, intermediates thereof and methods for preparation of same
    Patent number: 7687652
    Abstract: Novel cyclic and acyclic oxazaphospholanes are described, as well as their use in the synthesis of sphingomyelin and sphingomyelin analogous. The production of synthetic sphingomyelins is also described. 2S, 3R stereoisomers of oxazaphospholanes and sphingomyelins, and synthetic methods for their preparation are described.
    Type: Grant
    Filed: January 13, 2005
    Date of Patent: March 30, 2010
    Assignee: Biolab Ltd
    Inventors: Elimelech Rochlin, Jean Hildesheim, Alisa Berlin
  • Sphingolipids' Polyalkylamines Conjugates
    Publication number: 20080112917
    Abstract: The present invention concerns novel sphingolipid-polyalkylamines conjugates, a process for their preparation and pharmaceutical compositions comprising the same. In particular, the present invention concerns ceramide based polyalkylamine conjugates and its use as a capturing agent. A preferred ceramide polyalkylamine conjugate is a ceramide-spermine conjugate, more preferably, N-palmitoyl D-erythro sphingosyl-1-carbamoyl spermine.
    Type: Application
    Filed: June 17, 2004
    Publication date: May 15, 2008
    Applicants: BIOLAB LTD., YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM
    Inventors: Yechezkel Barenholz, Dmitri Simberg, Elimelech Rochlin
  • Sphingomyelin, Intermediates Thereof and Methods For Preparation Of Same
    Publication number: 20070282120
    Abstract: Novel cyclic and acyclic oxazaphospholanes are described, as well as their use in the synthesis of sphingomyelin and sphingomyelin analogous. The production of synthetic sphingomyelins is also described. 2S, 3R stereoisomers of oxazaphospholanes and sphingomyelins, and synthetic methods for their preparation are described.
    Type: Application
    Filed: January 13, 2005
    Publication date: December 6, 2007
    Inventors: Elimelech Rochlin, Jean Hildesheim, Alisa Berlin
  • Process for large scale preparation of sphingosines and ceramides
    Patent number: 6469148
    Abstract: Synthetic methods for convenient large scale preparation of D-erythro sphingosines and ceramides of high isomeric purity are described.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: October 22, 2002
    Assignee: Lipiderm Ltd.
    Inventor: Elimelech Rochlin