Patents by Inventor Eline FEYEN

Eline FEYEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINAZOLIN-4-ONE AND THIENO[2,3-D]PYRIMIDIN-4-ONE INHIBITORS OF ERBB4 (HER4) FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20240002351
    Abstract: The present invention relates to a compound of formula (I) or a stereoisomer, or tautomer, for use in the prevention or treatment of a disease associated with the activation of receptor tyrosine-protein kinase (erbB4). In formula (I), wherein n, A1, A2, A3, A4, A5, R1, R2, R3, and R4 have the same meaning as that defined in the claims and the description. The present invention also relates uses of such compounds for the prevention and/or treatment of a disease associated with the activation of receptor tyrosine-protein kinase (erbB-4) such as heart failure, metabolic disorders, inflammatory disorders, fibrotic disorders, and cancer. The present invention also provides pharmaceutical compositions comprising such compounds, as well as the use of the compounds as a medicament.
    Type: Application
    Filed: March 4, 2022
    Publication date: January 4, 2024
    Applicant: UNIVERSITEIT ANTWERPEN
    Inventors: Vincent Frans Maria SEGERS, Gilles Willy DE KEULENAER, Eline FEYEN, Hans Louis Jos DE WINTER