Patents by Inventor Eline Luning Prak

Eline Luning Prak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombination sequence (RS) rearrangement frequency as a measure of central B cell tolerance
    Patent number: 10837060
    Abstract: The invention relates to methods and materials for diagnosing an autoimmune disease such as SLE, Type 1 diabetes, and the like. More particularly, the invention relates to methods and materials for assessing the frequency of recombination sequence (RS) rearrangement as a novel marker for an autoimmune disease. Such an assay can allow clinicians to diagnose an autoimmune disease based on the RS rearrangement frequency in an autoimmune patient as compared to an otherwise healthy control. In addition, the method includes identifying individuals who are at increased risk of developing autoimmunity. The method may also be helpful in directing the type of therapy and monitoring the effects of therapy in patients with autoimmune or non-autoimmune conditions.
    Type: Grant
    Filed: August 10, 2015
    Date of Patent: November 17, 2020
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Anil K. Panigrahi, Eline Luning Prak
  • Recombination Sequence (RS) Rearrangement Frequency as a Measure of Central B Cell Tolerance
    Publication number: 20160017428
    Abstract: The invention relates to methods and materials for diagnosing an autoimmune disease such as SLE, Type 1 diabetes, and the like. More particularly, the invention relates to methods and materials for assessing the frequency of recombination sequence (RS) rearrangement as a novel marker for an autoimmune disease. Such an assay can allow clinicians to diagnose an autoimmune disease based on the RS rearrangement frequency in an autoimmune patient as compared to an otherwise healthy control. In addition, the method includes identifying individuals who are at increased risk of developing autoimmunity. The method may also be helpful in directing the type of therapy and monitoring the effects of therapy in patients with autoimmune or non-autoimmune conditions.
    Type: Application
    Filed: August 10, 2015
    Publication date: January 21, 2016
    Inventors: Anil K. Panigrahi, Eline Luning Prak
  • Recombination sequence (RS) rearrangement frequency as a measure of central B cell tolerance
    Patent number: 9115399
    Abstract: The invention relates to methods and materials for diagnosing an autoimmune disease such as SLE, Type 1 diabetes, and the like. More particularly, the invention relates to methods and materials for assessing the frequency of recombination sequence (RS) rearrangement as a novel marker for an autoimmune disease. Such an assay can allow clinicians to diagnose an autoimmune disease based on the RS rearrangement frequency in an autoimmune patient as compared to an otherwise healthy control. In addition, the method includes identifying individuals who are at increased risk of developing autoimmunity. The method may also be helpful in directing the type of therapy and monitoring the effects of therapy in patients with autoimmune or non-autoimmune conditions.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: August 25, 2015
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Anil K. Panigrahi, Eline Luning Prak
  • Recombination Sequence (RS) Rearrangement Frequency as a Measure of Central B Cell Tolerance
    Publication number: 20110182902
    Abstract: The invention relates to methods and materials for diagnosing an autoimmune disease such as SLE, Type 1 diabetes, and the like. More particularly, the invention relates to methods and materials for assessing the frequency of recombination sequence (RS) rearrangement as a novel marker for an autoimmune disease. Such an assay can allow clinicians to diagnose an autoimmune disease based on the RS rearrangement frequency in an autoimmune patient as compared to an otherwise healthy control. In addition, the method includes identifying individuals who are at increased risk of developing autoimmunity. The method may also be helpful in directing the type of therapy and monitoring the effects of therapy in patients with autoimmune or non-autoimmune conditions.
    Type: Application
    Filed: September 23, 2009
    Publication date: July 28, 2011
    Inventors: Anil K. Panigrahi, Eline Luning Prak